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A stereological analysis of collagen phagocytosis in a model of chronic inflammation in rats (Abstract)

  • D. A. Deporter
Part of the Inflammation: Mechanisms and Treatment book series (FTIN, volume 4)

Abstract

It is well established that the phagocytosis and intracellular degradation of collagen by fibroblasts is an important mechanism in the normal remodelling and turnover of a variety of soft connective tissues (Cate, T. and Deporter, D. A. (1975). Anat. Rec., 182, 1). Furthermore, using electron microscope stereology, we have recently demonstrated that there is a positive correlation between the collagen phagocytic activity of a tissue and its rate of mature collagen turnover (Svoboda, Shiga and Deporter. (1980). Anat. Rec. In press).

Copyright information

© MTP Press Limited 1980

Authors and Affiliations

  • D. A. Deporter
    • 1
  1. 1.Canada

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