Advertisement

Comparison between calcium pyrophosphate and monosodic urate induced inflammations of the palatal connective tissue

  • J. L. Jouvin
  • A. Daniel
Part of the Inflammation: Mechanisms and Treatment book series (FTIN, volume 4)

Abstract

Suspensions of calcium pyrophosphate (CPPD) and monosodic urate (MS) induce an inflammatory response when injected subcutaneously1,2. CPPD deposits in man induce arthritides called pseudogout. The arthritis of pseudo-gout may last from 1 to 4 weeks and is lower in intensity than the arthritis of gout induced by MSU crystal deposits3. The clinical differences between gout and pseudogout suggest that pathophysiological processes of these diseases may differ. It seems that CPPD and MSU crystals are not treated in the same way by the surrounding tissues and cells.

Keywords

Polymorphonuclear Leukocyte Gouty Arthritis Palatal Mucosa Calcium Pyrophosphate Pseudo Gout 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    MacCarty, D.J. and Kozini, F. (1976). An overview of cellular and molecular mechanism in crystal induced inflammation. Arthritis Rheum., 18, (Suppl.), 757 CrossRefGoogle Scholar
  2. 2.
    Denko, C. W. and Whitehouse, M. W. (1976). Experimental inflammation induced by naturally occuring microcristalline calcium salts. J. Rheumatol., 3, 54PubMedGoogle Scholar
  3. 3.
    Cats, A. and Van de Putte, L. B. A. (1977). Athritis: a clinical model of inflammation. In Bonta, I. L., Thompson, J. and Brunek(eds.) Inflammation: mechanisms and their impact on therapy. Agents Actions Suppl., 3, (Basel: Birkhäuser Verlay)Google Scholar
  4. 4.
    Daniel A. and Fournier, B. (1978). Quantitative parameters of carrageenin induced inflammation of guinea-pig palatal mucosa. J. Dent. Res., 57, Special Issue A, 223Google Scholar
  5. 5.
    Weibel, E. R., Kistler, G. S. and Scherle, W. F. (1966). Practical stereological methods for morphometric cytology. J. Cell Biol., 30, 23PubMedCrossRefGoogle Scholar
  6. 6.
    Weissmann, G. and Rita, G. (1972). Molecular basis of gouty inflammation: interaction of monosodium urate crystals with lysosomes and liposomes. Nature (London) New Biol., 240, 167CrossRefGoogle Scholar
  7. 7.
    Schumacher, H. R., Fishbein, P., Phelps, D., Tse, R. and Krauser, R. (1975). Comparison of sodium urate and calcium pyrophosphate crystals phagocytosis by polymorphonuclear leukocytes. Arthritis Rheum, 18, (Suppl.), 783PubMedCrossRefGoogle Scholar
  8. 8.
    Mandel, N. S. (1976). The structural basis of crystal induced membranolysis. Arthritis Rheum., 19, (Suppl.), 439PubMedCrossRefGoogle Scholar

Copyright information

© MTP Press Limited 1980

Authors and Affiliations

  • J. L. Jouvin
    • 1
  • A. Daniel
    • 1
  1. 1.France

Personalised recommendations