Abstract
Arachidonic acid is metabolized by rabbit peritoneal PMNs via both prostaglandin cyclo-oxygenase and fatty acid lipoxygenase pathways to yield a multiplicity of biologically active products. These activities have been well characterized for the prostaglandins and thromboxanes and recent attention has been directed to the activities of the many hydroxy substituted arachidonic acid metabolites including leukocyte chemotactic and chemokinetic stimulation and possible mediation of leukoctye aggregation1,2.
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References
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© 1980 MTP Press Limited
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Walker, J.R., Dawson, W. (1980). Inhibitory effect of benoxaprofen and BW 755C on rabbit PMN leukocyte lipoxygenase (Abstract). In: Willoughby, D.A., Giroud, J.P. (eds) Inflammation: Mechanisms and Treatment. Inflammation: Mechanisms and Treatment, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9423-8_38
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DOI: https://doi.org/10.1007/978-94-010-9423-8_38
Publisher Name: Springer, Dordrecht
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