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D-penicillamine in rheumatoid arthritis: fixed versus variable regimes

  • D. R. Blake
  • E. F. J. Ring
  • R. C. Bucknall
  • P. A. Bacon
Part of the Inflammation: Mechanisms and Treatment book series (FTIN, volume 4)

Abstract

D-penicillamine is of proven therapeutic value in the treatment of rheumatoid arthritis1, although the increased incidence of side effects associated with high dose regimes (greater than 1 g/per day) has encouraged clinicians to examine the response to lower doses.

Keywords

Rheumatoid Arthritis Plasma Viscosity Rheumatoid Arthritis1 High Dose Regime Variable Regime 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Multicenter Trial Group (1973). Controlled trial of D-pencillamine in severe rheumatoid arthritis. Lancet, 1, 275CrossRefGoogle Scholar
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    Day, A.T., Golding, J. R., Lee, P. N. and Butterworth, A. (1974). Pencillamine in rheumatoid disease: a long-term study. Br. Med. J., 1, 180PubMedCrossRefGoogle Scholar
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    Ropes, M. W., Bennett, G. A., Cobb, S., Jacox, R. and Jessar, R. (1958). Revision of diagnostic criteria for rheumatoid arthritis. Bull. Rheum. Dis., 9, 175PubMedGoogle Scholar
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    Ritchie, D. M., Boyle, J. A., McInnes, J. R., Jasani, K. M., Dalabos, T. C., Grieveson, P. and Buchanan, W. W. (1968). Clinical studies with an articular index for the assessment of joint tenderness in patients with rheumatoid arthritis. Q. J. Med., 147, 393Google Scholar

Copyright information

© MTP Press Limited 1980

Authors and Affiliations

  • D. R. Blake
    • 1
  • E. F. J. Ring
    • 1
  • R. C. Bucknall
    • 1
  • P. A. Bacon
    • 1
  1. 1.UK

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