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The use of thymopoietin as an anti-inflammatory agent (Abstract)

  • A. Sedgwick
  • P. A. Thrower
  • D. A. Willoughby
  • E. C. Huskisson
Part of the Inflammation: Mechanisms and Treatment book series (FTIN, volume 4)

Abstract

Following the use of levamisole as an anti-rheumatic drug and its postulated action via T suppressor cells, a study has been undertaken using thymopoietin. The preparation of thymopoietin used has been a synthetic pentapeptide. This has been found to have a significant effect on acute carrageenin pleurisy in that it caused a significant reduction in cell migration but had no effect on exudate volume. Thymopoietin also caused a reduction of the cotton pellet granuloma model. Preliminary results of a clinical trial in man show promising results.

Keywords

Public Health Clinical Trial Cell Migration Promising Result Suppressor Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© MTP Press Limited 1980

Authors and Affiliations

  • A. Sedgwick
    • 1
  • P. A. Thrower
    • 1
  • D. A. Willoughby
    • 1
  • E. C. Huskisson
    • 1
  1. 1.UK

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