Effect of synovial tissue on the matrix of articular cartilage in organ culture (Abstract)

  • R. W. Jubb
  • Honor B. Fell
Part of the Inflammation: Mechanisms and Treatment book series (FTIN, volume 4)


The experiments were made on the articular tissues of the metacarpophalangeal joints of young pigs. In organ culture the synovial tissue caused the breakdown of cartilage matrix1 and inhibited the synthesis of its sulphated proteoglycan2.


Articular Cartilage Organ Culture Synovial Tissue Sulphated Proteoglycan2 Press Limited 
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  1. 1.
    Fell, H. B. and Jubb, R. W. (1980). Arthritis Rheum., 20, 1359CrossRefGoogle Scholar
  2. 2.
    Jubb, R. W. and Fell, H. B. (1980). Arthritis Rheum. (In press)Google Scholar
  3. 3.
    Dingle, J.T., Saklatvala, J., Hembry, R., Tyler, J., Fell, H.B. and Jubb, R.W. (1979). Biochem. J., 184, 177PubMedGoogle Scholar

Copyright information

© MTP Press Limited 1980

Authors and Affiliations

  • R. W. Jubb
    • 1
  • Honor B. Fell
    • 1
  1. 1.UK

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