Lymphocytes bearing Fcγ receptors in rheumatoid arthritis: binding properties of the Fc receptors detected by Facb rosettes and ‘high avidity’ EA rosettes
The various immunological functions carried out by lymphocytes bearing receptors for the Fc portion of IgG (FcR) have become the subject of increasing research interest in recent years. These functions include regulation of the immune response1 and antibody-dependent (K cell) cytotoxicity2. Such cells may therefore be important in the pathogenesis of diseases such as rheumatoid arthritis (RA), in which aberrant immune responses and tissue damage mediated by immunological mechanisms play a significant role.
KeywordsRheumatoid Arthritis High Avidity Rosette Formation Myeloma Protein Leucocyte Migration Inhibition
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