The Electrical Basis for the Inhibitory Response of the Guinea Pig Internal Anal Sphincter to Nerve Stimulation and Drugs

  • S. P. Lim
  • T. C. Muir


The guinea pig internal anal sphincter (gpIAS) is innervated by three types of efferent nerves, cholinergic excitatory, adrenergic excitatory and non-adrenergic, non-cholinergic (NANC) inhibitory nerves, the transmitter for which is unknown (1).


Gastrointestinal Motility Field Stimulation Membrane Potential Change Spike Discharge Taenia Coli 
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© MTP Press Limited 1984

Authors and Affiliations

  • S. P. Lim
  • T. C. Muir

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