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A “Hot” Ground State Intermediate in the Photohydration of Pyrimidines

  • Shih Yi Wang
Conference paper
Part of the The Jerusalem Symposia on Quantum Chemistry and Biochemistry book series (JSQC, volume 10)

Abstract

Because the theme of this symposium concerns the excited state molecular species in organic and biochemistry and because you, the participants, are experts from diversified disciplines, this symposium provides an ideal forum for the discussion of a “hot” ground state intermediate in the photohydration of pyrimidines (Pyr). This is an issue which has confronted our laboratory ever since 1956. The general belief has been that the lifetime of a vibrationally excited or “hot” ground state Pyr (VPyro) is too short (~10−12 sec) for a photoreaction to take place. However, favorable evidence accumulated from our laboratory, as well as from others, has been considerable. Recently, this proposition has met with approval in the latest comprehensive review of Pyr photohydrates (Fisher and Johns, 1976). Therefore, first, I would like to discuss the nature of this photoreaction, second, the early background that led to my proposal, and third, the experimental findings which may be interpreted as being in favor of this proposal.

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Copyright information

© Springer Science+Business Media Dordrecht 1977

Authors and Affiliations

  • Shih Yi Wang
    • 1
  1. 1.School of Hygiene and Public Health, Division of Radiation Chemistry, Department of BiochemistryThe Johns Hopkins UniversityUSA

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