Mixed Diarrhoeal Infection in Calves: The Relative Importance of 2 Interacting Enteropathogens

  • Saul Tzipori
Part of the Current Topics in Veterinary Medicine and Animal Science book series (CTVM, volume 13)


Some of the causes of neonatal diarrhoea in suckling calves aged up to 10 weeks were examined. The susceptibility of calves to the diarrhoea-inducing effect of calf rotavirus was found to be age dependent. Calves over 6 days old were resistant to clinical diarrhoea although they did excrete virus in their faeces and subsequently developed antibody to rotavirus. An enterotoxigenic E. coli (ETEC) inoculated orally into either gnotobiotic or suckling calves aged 1 to 26 days did not cause diarrhoea. In contrast, diarrhoea was consistently produced in gnotobiotic and suckling calves between one and 15 days of age when they were inoculated with both calf rotavirus and ETEC. In general, diarrhoea appeared after a rotavirus incubation period of approximately 3 days and was independent of the order in which the 2 microbial agents were given.


Neonatal Diarrhoea Field Outbreak Suckled Beef Moredun Research Institute Suckling Calf 
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Copyright information

© ECSC, EEC, EAEC, Brussels-Luxembourg 1981

Authors and Affiliations

  • Saul Tzipori
    • 1
    • 2
  1. 1.‘Attwood’ Veterinary Research LaboratoryMelbourneAustralia
  2. 2.Moredun Research InstituteEdinburghUK

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