Postpneumonectomy pulmonary edema

  • Richard M. Peters
Part of the Developments in Critical Care Medicine and Anaesthesiology book series (DCCA, volume 1)


Edema occurs when there is net filtration of fluid from the capillaries. To explain postpneumonectomy pulmonary edema requires analysis of the factors which lead to filtration. These factors have been defined in the Starling equation [1,2].


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  1. 1.
    Starling EH: On the absorption of fluids from the connective tissue spaces. J Physiol 19:312 –326,1896.PubMedGoogle Scholar
  2. 2.
    Pappenheimer JR, Soto-Rivera A: Effective osmotic pressure of the plasma proteins and other quantities associated with the capillary circulation in the hind limbs of cats and dogs. Am J Physiol 152: 471–491, 1948.PubMedGoogle Scholar
  3. 3.
    Staub NC: Extravascular forces in lung affecting fluid and protein exchange. Am Rev Respir Dis 115: 159–163, 1977.PubMedGoogle Scholar
  4. 4.
    Taylor AE, Grimbert F, Rutili G, Kvietys PR, Parker JC: Pulmonary edema: changes in Starling forces and lymph flow. In: Hargens AR (ed) Tissue fluid pressure and composition, ch 14. Baltimore: Williams and Wilkins, 1981.Google Scholar
  5. 5.
    Hutchin P, Terzi RG, Hollandsworth LC, Johnson G Jr, Peters RM: The influence of intravenous fluid administration on postoperative urinary water and electrolyte excretion in thoracic surgical patients. Ann Surg 170: 813–823, 1969.PubMedCrossRefGoogle Scholar
  6. 6.
    Virgilio RW, Rice CL, Smith DE, James DR, Zarins CK, Hobelman CF, Peters RM: Crystalloid vs colloid resuscitation: is one better? A randomized clinical study. Surgery 85: 129–139, 1979.PubMedGoogle Scholar
  7. 7.
    Zarins CK, Rice CL, Peters RM, Virgilio RW: Lymph and pulmonary response to isobaric reduction in plasma oncotic pressure in baboons. Circ Res 43: 925–930, 1978.PubMedCrossRefGoogle Scholar
  8. 8.
    Snashall PD, Weidner WJ, Staub NC: Extravascular lung water after extracellular fluid volume expansion in dogs. J Appl Physiol (Respir Environ Exerc Physiol) 42: 624–629, 1977.Google Scholar
  9. 9.
    Staub NC: Pulmonary edema due to increased microvascular permeability to fluid and protein. Circ Res 43: 143–151, 1978.PubMedCrossRefGoogle Scholar
  10. 10.
    Erdmann AJ III, Vaughan TR Jr, Brigham KL, Wollverton WC, Staub NC: Effect of increased vascular pressure on lung fluid balance in unanesthetized sheep. Circ Res 37: 271–284, 1975.PubMedCrossRefGoogle Scholar
  11. 11.
    Gibbon JH Jr, Gibbon MH: Experimental pulmonary edema following lobectomy and plasma infusion. Surgery 12: 694–704, 1942.Google Scholar
  12. 12.
    Ohkuda K, Nakahara K, Weidner WJ, Binder A, Staub NC: Lung fluid exchange after uneven pulmonary artery obstruction in sheep. Circ Res 43: 152–161, 1978.PubMedCrossRefGoogle Scholar
  13. 13.
    Hultgren HN, Robinson MC, Wuerflein RD: Overperfusion pulmonary edema. Circulation [Suppl 3] 33 and 34: 132–133, 1966.Google Scholar
  14. 14.
    Fein A, Grossman RF, Jones JG. Overland E, Pitts L, Murray JF, Staub NC: The value of edema fluid protein measurement in patients with pulmonary edema. Am J Med 67: 32–38, 1979.PubMedCrossRefGoogle Scholar
  15. 15.
    Mellins RB, Levine R, Skalak R, Fishman AP: Interstitial pressure of the lung. Circ Res 24: 187–212. 1969.CrossRefGoogle Scholar
  16. 16.
    Pang LM, Rodriguez-Martinez F, Stalcup SA, Mellins RB: Effect of hyperinflation and atelectasis on fluid accumulation in the puppy lung. J Appl Physiol (Respir Environ Exerc Physiol) 45: 284–288, 1978.Google Scholar
  17. 17.
    Goldberg HS: Effect of lung volume history on rate of edema formation in isolated canine lobe. J Appl Physiol (Respir Environ Excrc Physiol) 45: 880–884, 1978.Google Scholar
  18. 18.
    Goldberg HS, Mitzner W, Batra G: Effect of transpulmonary and vascular pressures on rate of pulmonary edema formation. J Appl Physiol (Respir Environ Exerc Physiol) 43: 14–19, 1977.Google Scholar
  19. 19.
    G, Hauge A, Nicolaysen G: Alveolar pressure and lung volume as determinants of net transvascular fluid filtration. J Appl Physiol (Respir Environ Exerc Physiol) 42: 476–482, 1977.Google Scholar
  20. 20.
    Taylor AE: Capillary fluid filtration. Starling forces and lymph flow. Circ Res 49: 557–575, 1981.PubMedCrossRefGoogle Scholar
  21. 21.
    Hultgren HN: High altitude pulmonary edema. In: Staub NC (ed) Lung water and solute exchange, ch 15. New York: Marcel Dekker, 1978.Google Scholar
  22. 22.
    Hackett PH, Greagh CE, Grover RF, Honigman B, Houston CS, Reeves JT, Sophocles AM, Van Hardenbrock M: High-altitude pulmonary edema in persons without the right pulmonary artery. N Engl J Med 302: 1070–1073, 1980.PubMedCrossRefGoogle Scholar
  23. 23.
    Burrows B, Harrison RW, Adams WE, Humphreys EM, Long ET, Reimann AF: The postpneumonectomy state. Clinical and physiologic observations in thirty-six cases. Am J Med 28: 281–297, 1960.PubMedCrossRefGoogle Scholar

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© Springer Science+Business Media Dordrecht 1982

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  • Richard M. Peters

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