Pulmonary arterial pressure and gas exchange during thoracotomy

  • Lars Nordström
Part of the Developments in Critical Care Medicine and Anaesthesiology book series (DCCA, volume 1)


Uptake of oxygen and elemination of carbon dioxide depend on alveolar ventilation, pulmonary blood flow and a suitable regional distribution of ventilation in relation to blood flow. Thoracotomy influences on all these factors in a complicated manner. Results obtained from patients undergoing lung surgery can therefore be difficult to interpret, but on the other hand the use of endobronchial tube gives a physiologically interesting opportunity to measure ventilation-perfusion relationships of a defined region, namely, that of each lung.


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  1. 1.
    Aalto-Setälä M, Heinonen J, Salorinne Y: Cardiorespiratory function during thoracic anaesthesia: a comparison of two-lung ventilation and one-lung ventilation with and without PEEPS. Acta Anaesthesiol Scand 19: 287–195, 1975.PubMedCrossRefGoogle Scholar
  2. 2.
    Browne RA, Catton DV, Ashworth EJ: A study of oxygenation during thoracotomy. Can Anaesth Soc J 15: 468–477, 1968.PubMedCrossRefGoogle Scholar
  3. 3.
    Edwards EM, Hatch DJ: Experiences with double-lumen tubes. Anasthesia 20: 461–467, 1965.CrossRefGoogle Scholar
  4. 4.
    Hughes JMB, Glazier JB, Maloney JE, West JB: Effect on lung volume on the distribution of pulmonary blood flow in man. Respir Physiol 4: 58–72, 1968.PubMedCrossRefGoogle Scholar
  5. 5.
    Kerr JH, Crampton Smith A, Prys-Roberts C, Maloche R: Observations during endobronchial anaesthesia. I: Ventilation and carbon dioxide clearance. Br J Anaesth 45: 159–167, 1973.PubMedCrossRefGoogle Scholar
  6. 6.
    Kerr JH, Crampton Smith A, Prys-Roberts C, Meloche R, Foëx P: Observations during endobronchial anaesthesia. II: Oxugenation. Br J Anaesth 46: 84–92, 1974.PubMedCrossRefGoogle Scholar
  7. 7.
    Khanam T, Brantwaite MA: Arterial oxygenation during one-lung anaesthesia (1). Anaesthesia 28: 132–138, 1973.PubMedCrossRefGoogle Scholar
  8. 8.
    Khanam T, Brantwaite MA: Arterial oxygenation during one-lung anaesthesia (2). Anaesthesia 28: 280–290, 1973.PubMedCrossRefGoogle Scholar
  9. 9.
    Lunding M, Fernandes A: Arterial oxygen tension and acid-base status during thoracic anaesthesia. Acta Anaesthesiol Scand 11: 43–55, 1967.CrossRefGoogle Scholar
  10. 10.
    Nilsson E, Slater EM, Greenberg J: The cost of the quiet lung: fluctuations in PaO2 when the Carlens tube is used in pulmonary surgery. Acta Anaesthesiol Scand 9: 49–55, 1956.CrossRefGoogle Scholar
  11. 11.
    Nunn JF: The distribution of inspired gas during thoracic surgery. Ann R Coll Surg Engl 28: 223–237, 1961.PubMedCentralPubMedGoogle Scholar
  12. 12.
    Rehder K, Sessler AD: Function of each lung in spontaneously breathing man anaesthetized with thiopental-meperidine. Anesthesiology 38: 320–327, 1973.PubMedCrossRefGoogle Scholar
  13. 13.
    Seed RF: The cost of the quiet lung? Proc R Soc Med 60: 750–752, 1967.PubMedCentralPubMedGoogle Scholar
  14. 14.
    Tarhan S, Lundborg RO: Blood gas and pH studies during use of the Carlens catheter. Can Anaesth Soc J 15: 458–467, 1968.PubMedCrossRefGoogle Scholar
  15. 15.
    Tarhan S, Lundborg RO: Effects of increased expiratory pressure on blood gas tensions and pulmonary shunting during thoracotomy with use of the Carlens catheter. Can Anaesth Soc J 17: 4–11, 1970.PubMedCrossRefGoogle Scholar
  16. 16.
    Torda TA, McCulloch CH, O’Brien HD, Wright JS, Horton DA: Pulmonary venous admixture during one-lung anaesthesia. Anaesthesia 29: 272–279, 1974.PubMedCrossRefGoogle Scholar
  17. 17.
    Virtue RW, Permutt S, Tanaka R, Pearcy C, Bane HN, Bromberger-Barnea B: Ventilation- perfusion changes during thoracotomy. Anesthesiology 27: 132–146, 1966.CrossRefGoogle Scholar
  18. 18.
    Werner O, Malmkvist G, Nordstrom L: International Congress Series no. 533. Amsterdam- Oxford-Princetori, 1980, p 226.Google Scholar
  19. 19.
    West JB, Dollery CT, Naimark A: Distribution of blood flow in isolated lung: relation to vascular and alveolar pressures. J Appl Physiol 19: 713–724, 1964.PubMedGoogle Scholar
  20. 20.
    Wulff KE, Aulin I: Regional lung function in the lateral decubitus position. Acta Anaesthesiol Scand 16: 195–205, 1972.PubMedCrossRefGoogle Scholar

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© Springer Science+Business Media Dordrecht 1982

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  • Lars Nordström

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