Cytotoxic Inducers in Crohn’s Disease and Ulcerative Colitis

  • G. L. Gitnick
Part of the Developments in Gastroenterology book series (DIGA, volume 3)


The concept that infectious agents might be causative factors for Crohn’s disease (CD) was first proposed by Crohn et al (1) and for ulcerative colitis (UC) by Bargen (2). Further impetus to research in this area was provided by the reports of Mitchell and Rees (3) and Cave et al (4) that small (less than 220nm) transmissible agents from human tissues induced changes similar to IBD in mice and rabbits.


Inflammatory Bowel Disease Ulcerative Colitis Tissue Culture System Feline Infectious Peritonitis Feline Infectious Peritonitis Virus 
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Copyright information

© Martinus Nijhoff Publishers, The Hague 1982

Authors and Affiliations

  • G. L. Gitnick

There are no affiliations available

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