Abstract
A generally applicable process for the production of enan-tioraerically pure amino acids is described. The method is based upon an enzymic resolution of DL-amino acid amides. As a biocatalyst aminopep-tidase from Pseudomonas putida is used, which will stereospecifically hydrolyze the L-from of the amino acid amide. Efficient methods for the synthesis of substrates, the separation of L-amino acid from D-amino acid amide and the racemization and recycling of the unwanted isomer have been developed.
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© 1986 D. Reidel Publishing Company
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Boesten, W.H.J. et al. (1986). Efficient Enzymic Production of Enantiomerically Pure Amino Acids. In: Schneider, M.P. (eds) Enzymes as Catalysts in Organic Synthesis. NATO ASI Series, vol 178. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4686-6_24
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DOI: https://doi.org/10.1007/978-94-009-4686-6_24
Publisher Name: Springer, Dordrecht
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