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Heterocyst Envelope Glycolipids

  • Koichiro Awai
  • Sigal Lechno-Yossef
  • C. Peter Wolk
Part of the Advances in Photosynthesis and Respiration book series (AIPH, volume 30)

Summary

Heterocyst-forming cyanobacteria simultaneously photosynthesize, producing oxygen (O2), and fix dini-trogen (N2), initially into ammonia, using nitrogenase enzymes that are rapidly inactivated by O2. These cyanobacteria enable nitrogenases to function in an oxic environment by segregating them within specialized cells, called heterocysts, in which O2 is not produced, respiration is highly active, and an envelope barrier of glycolipids greatly slows the rate of entry of O2. We will describe the chemical structure of the heterocyst-specific glycolipids (Hgls), their physiological role, and what is known of their deposition. We will then discuss the clustered genes that encode the proteins required for their biosynthesis, how the glycolipids are believed to be synthesized, and what is known of the regulation of their biosynthesis. Finally, we will examine the relationship between their biosynthetic enzymes and other polyketide synthases, with an emphasis on those from cyanobacteria.

Keywords

Acyl Carrier Protein Acyl Transferase Nitrogen Deprivation Heterocyst Differentiation Biotin Carboxyl Carrier Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

ACP

Acyl carrier protein

AT

Acyl trans-ferase

KS

β-ketoacyl synthase

CLF

Chain length factor

cAMP

Cyclic adenosine monophosphate

DH

Dehy-drase

ER

Enoyl reductase

FAS

Fatty acid synthase

Hgl

Heterocyst envelope glycolipid

HGL or HGL layer

Laminated layer of Hgls

HEP

Layer of heterocyst envelope polysaccharide

KR

Ketoacyl reductase

PKS

Polyketide synthase

PUFA

Polyunsaturated fatty acid

TER

Thioester reductase

Notes

Acknowledgments

We thank Jeff Elhai (Virginia Commonwealth University) for outstanding help with use of BioBike. This work was supported in part by a Grant-in-Aid for Young Scientists (B) (Nos. 19770025 and 21770033) to Koichiro Awai from the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan. Sigal Lechno-Yossef was supported by U.S. DOE agreement no. 384H963, and additional support was obtained under U.S. DOE grant DOE-FG02– 91ER20021 (Peter Wolk).

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Copyright information

© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  • Koichiro Awai
    • 1
  • Sigal Lechno-Yossef
    • 2
    • 3
  • C. Peter Wolk
    • 4
  1. 1.Division of Global Research LeadersShizuoka UniversitySuruga-kuJapan
  2. 2.Great Lakes Bioenergy Research CenterUniversity of WisconsinMadisonUSA
  3. 3.MSU-DOE Plant Research LaboratoryMichigan State UniversityEast LansingUSA
  4. 4.MSU-DOE Plant Research Laboratory and Department of Plant BiologyMichigan State UniversityEast LansingUSA

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