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Fatty Acid Biosynthesis in Plants — Metabolic Pathways, Structure and Organization

  • Adrian P. Brown
  • Antoni R. SlabasEmail author
  • John B. Rafferty
Part of the Advances in Photosynthesis and Respiration book series (AIPH, volume 30)

Summary

Progress in the elucidation of metabolic pathways for fatty acid and triacylglycerol biosynthesis in plants is reviewed, together with evidence for gene function. Research in this area is being driven by the importance of storage lipids as potential new raw materials to replace petrochemicals. Significant advances have been made in the structural analysis of a number of the soluble enzymes in these pathways but progress still has to be made on membrane-bound enzymes. Many of the enzymes of triacylglycerol biosynthesis have been identified but the relative importance of the acyl-CoA dependent and independent pathways remains to be determined. The role of particular isoenzymes in specific triacylglycerol assembly remains a major challenge together with determining higher orders of enzyme interaction and metabolic channeling.

Keywords

Fatty Acid Biosynthesis Unusual Fatty Acid Biotin Carboxylase Biotin Carboxyl Carrier Protein Phosphatidic Acid Phosphatase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

ACCase

Acetyl-CoA carboxylase

ACP

Acyl-carrier protein

CoA

Coenzyme A

DGAT

Diacylglycerol acyltransferase

FAS

Fatty acid synthase

GPAT

Glycerol-3-phosphate acyltransferase

PDAT

Phospholipid: diacylglycerol acyltransferase

LPAT

1-Acyl sn-glycerol-3-phosphate acyltransferase

Notes

Acknowledgments

The authors wish to thank the Biological and Biotechnology Research Council for supporting work in the Durham and Sheffield laboratories over the years. Specific acknowledgement is given by Antoni R. Slabas and Adrian P. Brown for support from the LINK “Renewable Raw Materials” programme for the work on Ricinus.

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Copyright information

© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  • Adrian P. Brown
    • 1
  • Antoni R. Slabas
    • 1
    Email author
  • John B. Rafferty
    • 2
  1. 1.School of Biological and Biomedical SciencesUniversity of Durham, South RoadDurhamUK
  2. 2.Krebs Institute for Biomolecular Research, Department of Molecular Biology and BiotechnologyUniversity of SheffieldSheffieldUK

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