Hepatitis B virus infection: serology and diagnostic techniques
Since the discovery of reproducible specific serologic markers in type B viral hepatitis initiated more than two decades ago (Blumberg et al., 1965, 1967; Prince, 1968), substantial progress has been achieved concerning the virus-related markers and immune response during infection and hence towards prevention of this wide-spread form of hepatitis. Many of the markers and the methods for their detection have now become recognized as standard diagnostic tools. Hepatitis B tests besides being currently used for primary patient care and prevention through screening practices are also effectively utilized in a considerable number of clinical and epidemiological research studies.
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