What Is Evidence-Based Medicine?
The introduction of the term “evidence-based medicine” (EBM) has been regarded as one of the most important paradigm shifts throughout medical history. The concept originally aimed to educate clinicians on how to perform and interpret scientific evidence in terms of assessment of credibility, critical appraisal of the results, and integration of scientific evidence in the everyday work. The practice of EBM entails the integration of the current best evidence in the clinical decision-making process in terms of the care of every individual patient. Today, finding the best possible evidence is closer than ever, and as researchers and clinicians of today, a deepened understanding of the EBM concept should be considered an obligation. This chapter presents the fundamental principles of EBM, provides methods for incorporating the EBM in the clinical work, and discusses future directions of EBM.
- 1.Aromataris E, Fernandez R, Godfrey CM, Holly C, Khalil H, Tungpunkom P. Summarizing systematic reviews: methodological development, conduct and reporting of an umbrella review approach. Int J Evid Based Healthc. 2015;13(3):132–40. https://doi.org/10.1097/xeb.0000000000000055.CrossRefPubMedGoogle Scholar
- 5.Bhandari M, Swiontkowski MF, Einhorn TA, Tornetta P 3rd, Schemitsch EH, Leece P, et al. Interobserver agreement in the application of levels of evidence to scientific papers in the American volume of the Journal of Bone and Joint Surgery. J Bone Joint Surg Am. 2004;86-a(8):1717–20.CrossRefGoogle Scholar
- 12.Green SHJ. Glossary of terms in the cochrane collaboration. The cochrane collaboration. 2015. http://www.cochrane.org/sites/deafault/files/uploads/glossary.pdf.
- 13.Guyatt G, Rennie D, Meade OM, Cook JD. Users’ guide to the medical literature: a manual for evidence-based clinical practice. Boston, MA: McGraw-Hill; 2014.Google Scholar
- 16.Lind J. A treatise of scurvy. In three parts. Containing an enquiry into the nature, causes and cure, of that disease. Together with a critical and chronological view of what has been published on the subject. Edinburgh: Printed by Sands, Murray, and Cochran; 1753.Google Scholar
- 18.Matthews J. Quantification and quest for medical certainty. Princetion, NY: Princeton University Press; 1995.Google Scholar
- 20.Murad MH, Montori VM, Ioannidis JP, Jaeschke R, Devereaux PJ, Prasad K, et al. How to read a systematic review and meta-analysis and apply the results to patient care: users’ guides to the medical literature. JAMA. 2014;312(2):171–9. https://doi.org/10.1001/jama.2014.5559.CrossRefPubMedGoogle Scholar
- 22.Paynter R, Banez LL, Berliner E, Erinoff E, Lege-Matsuura J, Potter S, et al. EPC methods: an exploration of the use of text-mining software in systematic reviews. Rockville, MD: Agency for Healthcare Research and Quality (US); 2016.Google Scholar
- 26.Straus ES, Glasziou P, Richardson W, Haynes R. Evidence-based medicine. How to practice and teach EBM. Edinburgh: Churchill Livingstone; 2005.Google Scholar