Bone and soft-tissue sarcomas are relatively rare conditions since they represent about 1% of all cancers. Unfortunately, the mortality rate is very high since the 5-year survival rate is about 50%; however prognosis is strongly correlated with the histopathological tumor grade. Treatments include surgery, neoadjuvant and adjuvant chemotherapy, and radiotherapy. The diagnostic flowchart includes planar X-rays, bone scan, CT, and MRI. MRI should be considered the imaging of choice due to the high soft-tissue contrast and the high accuracy in the detection of soft tissue and bone involvement . It is possible that in the next future this could be one of the principal applications of the hybrid PET/MRI tomography.
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