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Haut- und Schleimhauterkrankungen an der Vulva mit erhöhtem Krebsrisiko

  • Sigrid Regauer
  • Barbara Eberz
Chapter

Zusammenfassung

Die chronisch entzündlichen Erkrankungen Lichen sclerosus und Lichen planus an der Vulva werden oft nicht erkannt, fehlinterpretiert oder miteinander verwechselt. Leitsymptom des Lichen sclerosus ist quälender Juckreiz, Schmerzen stehen insbesondere beim Lichen planus im Vordergrund. Die vielfach unerkannten und daher auch unbehandelten Erkrankungen sind insbesondere beim mukosalen Lichen planus mit zum Teil hoher Morbidität und entzündlicher Vernarbung verbunden. Frühzeitige Behandlung (Reduktion des Entzündungsinfiltrats und dadurch der Aktivität) kann das Fortschreiten der Erkrankungen meist verhindern. Patientinnen sollten regelmäßige gynäkologische Kontrollen wahrnehmen, denn beide Erkrankungen haben ein gering erhöhtes Risiko für die Entwicklung eines HPV-negativen Vulvakarzinoms. Der differenzierten vulvären intraepithelialen Neoplasie (dVIN) kommt als aggressiver Vorläuferläsion besondere Bedeutung zu.

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Copyright information

© Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature 2018

Authors and Affiliations

  1. 1.Institut für PathologieMedizinische Universität GrazGrazÖsterreich
  2. 2.Gynäkologische Praxis und Referenzzentrum für VulvaerkrankungenMürzzuschlagÖsterreich

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