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Molecular biological tests

  • Enno Stürenburg
  • Norbert Gässler
  • Aline Schröder
  • Udo Reischl

Abstract

Molecular biological testing has become a mainstay in the repertoire of infectious disease diagnostics like in no other field of medicine. Direct pathogen detection primarily relies upon two main methods: the polymerase chain reaction (PCR) and immunochromatography – often supplied as test strips or test cards. Alongside pathogen detection, the PCR method has the advantage that it can simultaneously analyze resistance determinants and/or virulence factors. In the age of multidrug-resistant (nosocomial) pathogens, rapid and reliable molecular biological differentiation is becoming increasingly important given the urgency indicated to effectively isolate affected patients at the earliest possible chance.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Enno Stürenburg
    • 1
  • Norbert Gässler
    • 2
  • Aline Schröder
    • 3
  • Udo Reischl
    • 4
  1. 1.Dr. Staber & KollegenHamburgGermany
  2. 2.Zentrum für Labordiagnostik, St. Bernward-KrankenhausHildesheimGermany
  3. 3.Med-Lab Medizinische Dienstleistungs GmbHHamburgGermany
  4. 4.Universitätsklinikum RegensburgInstitut für Medizinische Mikrobiologie und HygieneRegensburgGermany

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