Keimzelltumoren bei Kindern

Chapter

Zusammenfassung

Zu den seltenen intrakraniellen Tumoren gehören diejenigen mit Abstammung aus der Keimbahn. In Europa rechnet man mit 0,3–0,5 %, in Asien ist der Tumor allerdings mit bis zu 15 % sehr häufig. Der höchste Altersgipfel liegt in der Kindheit und nach Beginn der Pubertät. Die Tumoren haben Ähnlichkeit mit Keimbahntumoren der Gonaden und werden im Bereich der Mittellinienstrukturen beobachtet. Neben benignen Teratomen (WHO-Grad I) sind am häufigsten maligne Germinome. Diese Tumoren, mit der Pinealis als Hauptmanifestationsort (50 %), gelten als gut strahlensensibel, es gibt gut dokumentierte Chemotherapieprotokolle. Die Kenntnis der embryonalen Entstehung und das Langzeit-Outcome sind wichtig für die modernen kinderneurochirurgischen und interdisziplinären Behandlungsregimes.

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© Springer-Verlag Berlin Heidelberg 2018

Authors and Affiliations

  1. 1.Schwerpunkt Kinderneurochirurgie Neurochirurgische Klinik, Operatives Kinderzentrum OPKiZUniversitätsmedizin GöttingenGöttingenDeutschland

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