COPD pp 189-193 | Cite as

Asthma-COPD Overlap Syndrome

  • Chin Kook RheeEmail author


Although asthma and COPD are characterized by reversible airway obstruction and by persistent airway obstruction, respectively, these two features are not mutually exclusive. Thus, some patients may show both characteristics of asthma and COPD. For example, if a patient shows positive for bronchodilator test and post-bronchodilator FEV1 (forced expiratory volume in 1 s)/FVC (forced vital capacity) < 0.7 at the same time, the patient meets both characteristics of asthma and COPD. Asthma is clinically characterized by respiratory symptoms such as wheeze, shortness of breath, chest tightness, and cough [1]. However, these clinical characteristics are also frequently observed in patients with COPD, too. Patients who showed overlapped feature of asthma and COPD have been always existed. However, these patients have been usually excluded in clinical trial of asthma or COPD. Many experts of each filed (asthma and COPD) sometimes denied the existence of these patients and considered them only as heterogeneity of each disease. However, since these patients definitely exist, the concept of asthma-COPD overlap syndrome (ACOS) has emerged recently.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  1. 1.Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal MedicineSeoul St. Mary’s Hospital, College of Medicine, The Catholic University of KoreaSeoulSouth Korea

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