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Enzyme pp 649-657 | Cite as

Aconitase

[4.2.1.3 Citrat (Isocitrat)-Hydrolyase (Aconitat-Hydratase).]
  • John Francis Morrison
Chapter
Part of the Handbuch der Physiologisch- und Pathologisch-Chemischen Analyse book series (HOPPE-SEYLER)

Zusammenfassung

The enzyme which catalyses the equilibrium expressed by the reaction
was discovered by Martitts and Knoop 1 and named aconitase by Breusch 2. It has been suggested that two enzymes are concerned in catalysing this reaction3–8, but although aconitase has not been isolated in the pure state, the available evidence indicates that only a single enzyme is involved9–16. Recently, it has been established that of the four stereo¬isomers of isocitric acid only the dextrorotatory ls isomers occurs naturally17. (Lg corre¬sponds to the configuration of the a carbon of naturally occurring serine.)

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Copyright information

© Springer-Verlag Berlin Heidelberg 1967

Authors and Affiliations

  • John Francis Morrison
    • 1
  1. 1.Department of Biochemistry, John Curtin School of Medical ResearchThe Australian National UniversityCanberraAustralia

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