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Enzyme pp 498-502 | Cite as

Oxalacetic decarboxylase and related enzymes

  • Merton F. Utter
Chapter
Part of the Handbuch der Physiologisch- und Pathologisch-Chemischen Analyse book series (HOPPE-SEYLER)

Zusammenfassung

This section will deal with methods for determining enzymes which decarboxylate oxalacetate (OA) or form the latter substance by CO2 fixation. Three types of enzymes will be considered: (a) those enzymes which decarboxylate OA to pyruvate and CO2 (Reaction 1) and which may be considered true decarboxylases, (b) the plant and bacterial enzyme which catalyzes the irreversible formation of OA from phosphoenolpyruvate (PEP) and CO2 (Reaction 2), and which is termed here PEP carboxylase, and (c) the enzyme from animal tissues or microorganisms which catalyzes the reversible formation of OA from PEP, CO2, and a nucleotide diphosphate (Reaction 3) and which is called here PEP carboxykinase.

Abbreviations

ADP

adenosine diphosphate

ATP

adenosine triphosphate

ATP

ase adenosine triphosphatase

DPNH

reduced diphosphopyridine nucleotide

GDP

guanosine diphosphate

GSH

reduced glutathione

GTP

guanosine triphosphate

IDP

inosine diphosphate

ID

Pase inosine diphosphatase

ITP

inosine triphosphate

OA

oxalacetate

PEP

phosphoenolpyruvate

Pi

inorganic phosphate.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1967

Authors and Affiliations

  • Merton F. Utter
    • 1
  1. 1.Department of BiochemistryWestern Reserve University School of MedicineClevelandUSA

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