The Effect of Staphylococcal α-Toxin on Blood Platelets

  • K. Mašek
  • J. Libánská
  • R. Nosál
  • H. Rašková


Staphylococcal α-toxin incubated with rabbit blood platelets induces an early blood platelet aggregation with subsequent release of 5-HT. The phenomenon of platelet aggregation is accompanied by release of ATPase activity into the supernatant. An electron microscope examination of platelets after the addition of toxin revealed characteristic morphological changes.


Staphylococcal α-toxin Blood Platelets Aggregation 5-hydroxytryptamine 


Staphylokokkentoxin α Blutplättchen Aggregation 5 Hydroxytryptamin 


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Copyright information

© Springer-Verlag Berlin Heidelberg 1969

Authors and Affiliations

  • K. Mašek
    • 1
  • J. Libánská
    • 1
  • R. Nosál
    • 1
  • H. Rašková
    • 1
  1. 1.Institute of Pharmacology Czechoslovak Academy of Sciences and Faculty of PediatricsCharles UniversityPrague 2ČSSR

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