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Biochemical and Histochemical Studies on Histamine in the Digestive Tract: Distribution in Different Chordates and Cellular Stores in the Dog / Biochemische und histochemische Untersuchungen zur Lokalisation von Histamin im Verdauungstrakt

  • W. Lorenz
  • A. Schauer
  • St. Heitland
  • E. Matekja
  • E. Werle
Chapter

Abstract

The histamine contents of the stomach and other organs of the digestive tract of chordates were determined by two fluorometric assay procedures [2, 3] and by the biological assay of histamine on the isolated guinea-pig ileum, the response of which could be inhibited completely by antazoline. As mean values μg histamine dihydrochloride/g wet weight) were found in the corpus and antral mucosa: man 17.3, 5.3; dog: 88.0, 53.0; pig: 99.7, 102.0; cow (rennet-bag): 43.6, 30.0; guinea-pig: 12.7, 12.5; hen: 41.5, 21.9; pigeon (corpus): 13.9; tortoise: 11.2, 3.0; lizard: 15.6, 15.6: frog (whole stomach): 2.5; trout: 5.8, 5.4; catfish: 9.1, 1.9; dogfish: 7.4, 7.8; thornback (raja stellaris): 4.8, 5.5; ciona intestinalis (whole stomach): 1.8; halocynthia papillosa (whole stomach): 1.2.

References

  1. 1.
    Enerbäck, L.: Acta path, microbiol. scand. 66, 313 (1966).Google Scholar
  2. 2.
    Lorenz, W.: Thesis, University of Munich 1969, p. 98.Google Scholar
  3. 3.
    Shore, P.A., A. Burkhalter, and V.H. Cohn, Jr.: J. Pharmacol. exp. Ther. 127, 182 (1959).PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1969

Authors and Affiliations

  • W. Lorenz
    • 1
  • A. Schauer
  • St. Heitland
  • E. Matekja
  • E. Werle
  1. 1.Inst. für Klinische Chemie und Klinische Biochemie der UniversitätMünchen 15Deutschland

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