Occurrence and Properties of Diamine Oxidases in Salivary Glands and Gastric Mucosa of Man and other Mammals / Vorkommen und Eigenschaften von Diaminoxydasen in Speicheldrüsen und Magen des Menschen und verschiedener Säugetiere
In the salivary glands of different species diamine oxidases (DAO) (diamine: O2-oxidoreductases EC 22.214.171.124) could be demonstrated by the method of Lorenz et al. [2, 3] and Holmstedt and Tham . The activities of these enzymes with 2.5 × 10−3 M cadaverine as substrate in the submaxillary glands of man, dog, pig and cow were 0.11 ± 0.08; 0.13 ± 0.09; 0.07 ± 0.03 and 0.11 ± 0.05 mU/mg biuret protein of the homogenate, in the parotid glands of dog, pig and cow 0.06 ± 0.05; 0.17 ± 0.07 and 0.26 ± 0.10. In the gastric mucosa DAO could be found only in cow, rat and dog, but not in man, pig, cat and guinea pig. The activities using 1 × 10−3 M histamine as substrate were very low (in cow, rat and dog 0.026, 0.01 and 0.006 mU/mg protein).