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Der Internist pp 438-444 | Cite as

Pathogenetische Bedeutung von Rezeptoren bei Asthma bronchiale

  • F. V. Kohl
Chapter

Zusammenfassung

Beim Asthma bronchiale wird eine angeborene oder erworbene verminderte Kapazität der beta-2-adrenergen Rezeptoren innerhalb des Bronchialsektors diskutiert, woraus Hyperreaktivität der Atemwege und Bronchokonstriktion folgen sollen, da nun ein Ungleichgewicht zu alpha-adrenergen und cholinergen Rezeptoren besteht. Anhand der zur Verfügung stehenden Daten wird dargelegt, ob es sich tatsächlich beim Astma bronchiale im Blick auf die Ursache um eine Rezeptorstörung handeln kann, was anhand folgender Abschnitte entwickelt wird: Verhältnisse bei normalem Ruhetonus der Atemwege, Einfluß von Inflammation und Schleimhautsekretion auf das cholin-adrenerge Gleichgewicht, cholinerger und adrenerger Rezeptor-Status beim Asthma bronchiale, Einfluß von Erregern, von Antikörpern und von Pharmaka auf die beta-Rezeptoren.

Schlüsselwörter

Sympathikus Parasympathikus adrenerge Rezeptoren cholinerge Rezeptoren Katecholamine α-Rezeptoren β1, β2 Rezeptoren 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • F. V. Kohl
    • 1
  1. 1.Medizinische Poliklinik, Zentrum für Innere MedizinPhilipps-Universität MarburgMarburgDeutschland

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