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Der Internist pp 390-396 | Cite as

Insulinrezeptordefekte als Krankheitsursache

  • M. Dreyer
  • H. W. Rüdiger
Chapter

Zusammenfassung

Immer mehr verdichtet sich die Erkenntnis, daß der Typ-II-Diabetes überwiegend auf eine verminderte Insulinempfindlichkeit zurückzuführen ist und daß einer solchen auch noch andere Krankheitsbilder zugrunde liegen. Der Blick richtet sich zunächst auf die Pathophysiologie und Klinik der Insulinresistenz und anschließend auf die genetischen wie auch erworbenen Defekte der Insulinrezeptoren, um schließlich unter dem Blickwinkel der besonderen Stoffwechselsituation den Standpunkt der Therapie neu zu definieren.

Schlüsselwörter

Diabetes mellitus Insulinresistenz Insulinrezeptor 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • M. Dreyer
    • 1
  • H. W. Rüdiger
    • 2
  1. 1.Krankenhaus BethanienHamburg 20Deutschland
  2. 2.Arbeitsgruppe ToxikogenetikOrdinariat für Arbeitsmedizin der Universität HamburgDeutschland

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