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Der Internist pp 372-389 | Cite as

Rezeptoren im Lipoprotein-Stoffwechsel

  • A. Steinmetz
  • G. Utermann
Chapter

Zusammenfassung

Heute werden neben dem etablierten und sehr gut definierten LDL-Rezeptorsystem mehrere weitere Rezeptoren im Lipoproteinstoffwechsel diskutiert, deren endgültige Darstellung noch aussteht: speziell der Apolipoprotein-E- oder Remnant-Rezeptor, der sogenannte Acetyl-LDL-Rezeptor als Rezeptor für modifizierte LDL, der High-Density-Lipoprotein-Rezeptor und der β-Very-Low-Density-Lipoprotein-Rezeptor. Die Daten über die letztgenannten Rezeptoren sind zum Teil noch kontrovers und erwarten eine endgültige Klärung in der Zukunft. Die vorliegende Übersicht hat das Ziel, sowohl die mittlerweile etablierten als auch die noch in der Diskussion sich befindenden Daten über die Lipoprotein-Rezeptorsysteme und ihre Liganden zusammenzufassen und ein Bild vom heutigen Verständnis darüber zu entwerfen.

Schlüsselwörter

Lipoproteinmeta-bolismus LDL-Rezeptor Apo-lipoproteine Arteriosklerose 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • A. Steinmetz
    • 1
  • G. Utermann
    • 2
  1. 1.Abteilung Endokrinologie und Stoffwechsel, Zentrum Innere MedizinUniversität MarburgMarburgDeutschland
  2. 2.Institut für medizinische Biologie und GenetikUniversität InnsbruckDeutschland

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