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Zusammenfassung

Das gleichzeitige Vorkommen von Niereninsuffizienz und Skeletterkrankung ist seit dem letzten Jahrhundert bekannt (LUCAS 1883; Förster 1887). Während LUCAS (1883) noch die Masturbation als Ursache der Knochenveränderungen vermutete, wurde diese von Förster (1887), CAMERON (1918), BARBER (1921, 1926) und PARSONS (1927) als sog. „renale Rachitis“ erkannt. Dieselben Autoren beschrieben auch erstmals die typischen klinischen Zeichen wie vermindertes Wachstum und Reifung des Skeletts, Auftreibungen der Gelenke und Deformitäten der langen Röhrenknochen.

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Literatur

  1. Abassi V, Lowe CU, Calgagno PL (1968) Oculo-cerebro-renal syndrome. Am J Dis Child 115:145.Google Scholar
  2. Agus ZS, Goldberg M (1972) Pathogenesis of uremic osteodystrophy. Radiol Clin North Am 10:545.PubMedGoogle Scholar
  3. Ahmed KY, Wills MR, Skinner RK, Varghese Z, Meinhard E, Baillod A, Moorhead JF (1976) Persistent hypophosphataemia and osteomalacia in dialysis patients not on oral phosphate-binders: response to dihydrotachysterol therapy. Lancet 2:439.PubMedGoogle Scholar
  4. Ahmed KY, Varghese Z, Meinhard E, Baillod RA, Skinner RK, Wills MR, Moorhead JF (1977) Hypophosphaturia and osteomalacia in hemodialysis patients not taking phosphate binders. In: Massry SG, Ritz E (eds) Phosphate metabolism. Plenum, New YorkGoogle Scholar
  5. Aksoy M, Camli N, Dincot K, Erdem S, Akgün T (1972) Osseous changes in Wilson’s disease — A radiologic study of nine patients. Radiology 102:505.PubMedGoogle Scholar
  6. Albright F, Drake TG, Sulkowitch HW (1937a) Renal osteitis cystica. Report of a case with discussion of metabolic aspects. Bull Johns Hopkins Hosp 60:311Google Scholar
  7. Albright F, Butler AM, Bloomberg E (1937b) Rickets resistant to vitamin D therapy. Am J Dis Child 54:529Google Scholar
  8. Albright F, Burnett CH, Parson W, Reifenstein EC, Roos A (1946) Osteomalacia and rickets: the various etiologies met in United States with emphasis on that resulting from a special form of acidosis: the therapeutic implications for each etiological subgroup and the relationship between osteomalacia and Milkman’s syndrome. Medicine (Baltimore) 25:399.Google Scholar
  9. Albright F, Reifenstein EC (1948) The parathyroid glands and metabolic bone disease. Williams and Wilkins, BaltimoreGoogle Scholar
  10. Alepa FP, Howell RR, Klinenberg JR, Seegmiller JE (1967) Relationships between glycogen storage disease and tophaceous gout. Am J Med 42:58.PubMedGoogle Scholar
  11. Alfrey AC, Jenkins D, Groth CG, Schorr WS, Gecelter L, Ogden SA (1968) Resolution of hyperparathyreoidism, renal osteodystrophy and metastatic calcification after renal homotransplantation. N Engl J Med 279:1349.PubMedGoogle Scholar
  12. Alfrey AC, Solomons C, Ciricillo J, Miller N (1976a) Evidence for abnormal pyrophosphate metabolism in uremia. J Clin Invest 57:692PubMedCentralPubMedGoogle Scholar
  13. Alfrey AC, Solomons C, Ciricillo J, Miller N (1976b) Bone pyrophosphate in uremia and its association with extraosseous calcification. J Clin Invest 57:700PubMedCentralPubMedGoogle Scholar
  14. Andersen DH, Schlesinger ER (1942) Renal hyperparathyroidism with calcification of the arteries in infancy. Am J Dis Child 63:102.Google Scholar
  15. Askew FA, Bourdillon RB, Bruce HM, Jenkins RGC, Webster TA (1931) The distillation of vitamin D. Proc R Soc Lond [Biol] 107:16.Google Scholar
  16. Astley R, Teall CG, Bickel H (1952) The radiology of Lignac-Fanconi disease. Acta Paediatr (Suppl 90, part IV) 41:98.Google Scholar
  17. Avioli LV, Teitelbaum SL (1976) The renal osteodystrophies. In: Brenner BM, Rector FC Jr (eds) The kidney, vol 2. Saunders,. LondonGoogle Scholar
  18. Baber MD (1956) A case of congenital cirrhosis of the liver with renal tubular defects akin to those in the Fanconi syndrome. Arch Dis Child 31:335.PubMedGoogle Scholar
  19. Ball J, Garner A (1966) Quantitative observations on mineralised and unmineralised bone in chronic renal azotaemia and intestinal malabsorption syndrome. J Path Bact 91:545.PubMedGoogle Scholar
  20. Balsan S (1976) Renal osteodystrophy. In: Liebermann E (ed) Clinical nephrology. Lippincott, Philadelphia TorontoGoogle Scholar
  21. Barber H (1921) Renal dwarfism. Q J Med 14:205.Google Scholar
  22. Barber H (1926) Renal dwarfism. A study of the course of the disease from seventeen cases. Guys Hosp Rep 76:307.Google Scholar
  23. Bauer B (1968) Debré-De Toni-Fanconi Syndrom mit Glykogenose der Leber. Klin Wochenschr 46:317.PubMedGoogle Scholar
  24. Bayley N, Pinneau SR (1952) Tables for predicting adult height from skeletal age: revised for use with the Greulich-Pyle hand standard. J Pediatr 40:423.PubMedGoogle Scholar
  25. Beale MG, Salcedo JR, Ellis D, Rao D (1976) Renal osteodystrophy. Pediatr Clin North Am 23:873.PubMedGoogle Scholar
  26. Bennett WM, Musgrave JE, Campbell RA, Elliot D, Cox R, Brooks RE, Lovrien EW, Beals RK, Porter GA (1973) The nephropathy of the nail-patella syndrome. Clinicopathologic analysis of 11 kindred. Am J Med 54:304.PubMedGoogle Scholar
  27. Bennett WM, Houghton DC, Beals RC (1980) Nephropathy of idiopathic multicentric osteolysis. Nephron 25:135.Google Scholar
  28. Bergstrom WH, Gardner LI (1969) Metabolic disorders with osseous lesions. In: Nelson WE, Vaughan VC, McKay RJ (eds) Textbook of Pediatrics. Saunders, PhiladelphiaGoogle Scholar
  29. Better OS (1980) Tubular dysfunction following kidney transplantation. Editorial review. Nephron 25:209.PubMedGoogle Scholar
  30. Betts PR, White RHR (1976) Growth potential and skeletal maturity in children with chronic renalinsufficiency. Nephron 16:325.PubMedGoogle Scholar
  31. Bickel H, Thursby-Pelham DC (1954) Hyperaminoaciduria in Lignac-Fanconi disease, in galactosemia and in an obscure syndrome. Arch Dis Child 29:224.PubMedGoogle Scholar
  32. Biervliet JPGM van, Donckerwolcke RAMG, Stekelenburg GJ van (1975) Sodium chloride restriction and extracellular fluid volume contraction in hyperphosphaturic vitamin D resistant rickets in the Lowe syndrome. Helv Paediatr Acta 30:365.Google Scholar
  33. Bordier P, Ryckwaert A, Marie P, Miravet L, Norman A, Rasmussen H (1977) Vitamin D metabolites and bone mineralization in man. In: Norman AW, Schaefer K, Coburn JW, DeLuca HF, Fraser D, Grigoleit HG, Herrath D von (eds) Vitamin D: biochemical, chemical and clinical aspects related to calcium metabolism, de Gruyter, BerlinGoogle Scholar
  34. Bosnjakovic S, Heuck F (1979) Röntgenmorphologie der Periostregion bei Osteopathien. Radiologe 19:307.PubMedGoogle Scholar
  35. Boudin G, Pépin B (1961) Osteoarticular changes in hepatolenticular degeneration in Wilson’s disease. In: Walshe JM, Cumings JN (eds) Some current concepts. Blackwell, OxfordGoogle Scholar
  36. Boyle IT, Miravet L, Gray RW, Holick MF, DeLuca HF (1972) The response of intestinal calcium transport to 25-hydroxy and 1,25-dihydroxy vitamin D in nephrectomized rats. Endocrinology 90:605.PubMedGoogle Scholar
  37. Boyle IT, Omdahl JL, Gray RW, DeLuca HF (1973) The biological activity and metabolism of 24, 25-dihydroxyvitamin D3. J Biol Chem 248:4174.PubMedGoogle Scholar
  38. Brailsford JF (1933) Slipping of epiphysis of the head of the femur. Its relation to renal rickets. Lancet 1:16.Google Scholar
  39. Bravo JF, Herman JH, Smyth CJ (1967) Musculoskeletal disorders after renal homotransplantation. A clinical and laboratory analysis of 60 cases. Ann Int Med 66:87.PubMedGoogle Scholar
  40. Brewer ED, Tsai H, Morris C (1977) Fanconi syndrome and its relationship to vitamin D. In: Norman et al. (eds) Vitamin D; Biochemical, chemical and clinical aspects to calcium metabolism, de Gruyter, BerlinGoogle Scholar
  41. Bricker NS, Slatopolsky E, Reiss E (1969) Cylcium, phosphorus and bone in renal disease and transplantation. Arch Int Med 123:543.Google Scholar
  42. Briggs WA, Kominami N, Merrill JP, Wislon RE (1972) Kidney transplantation in Fanconi syndrome. N Engl J Med 286:25.PubMedGoogle Scholar
  43. Brodehl J (1976) Tubular Fanconi syndromes with bone involvement. In: Bickel H, Stern J (eds) Inborn errors of calcium and bone metabolism. MTP Press, LancasterGoogle Scholar
  44. Brodehl J (1978) The Fanconi syndrome. In: Edelmann CM Jr (ed) Pediatric kidney disease vol II. Little Brown, BostonGoogle Scholar
  45. Brodehl J, Gellissen K, Hagge W (1969) The Fanconi syndrome in hepato renal glycogen storage disease. In: Peters GG, Roch-Ramel F (eds) Progress in nephrology. Springer, Berlin Heidelberg New YorkGoogle Scholar
  46. Broyer M, Kleinknecht C, Loirat C, Marti-Henneberg C, Roy MP (1974) Growth in children treated with long-term hemodialysis. J Pediatr 84:642.PubMedGoogle Scholar
  47. Broyer M, Kleinknecht C, Gagnadoux MF, Dartois AM (1977) Growth in uremic children. In: Strauss J (ed) Pediatric nephrology, vol IV. Garland, New YorkGoogle Scholar
  48. Broyer M, Kleinknecht C, Gagnadoux MF, Marti-Henneberg C, Dartois AM, Kermanach C, Ponliquen M, Degoulet P, Usberti M, Roy MP (1979) La croissance chez l’enfant traité par dialyse chronique. In: Grünfeld JP (ed) Actualités néphrologi-ques de l’Hôpital Necker. Flammarion, ParisGoogle Scholar
  49. Bulla M, Delling G, Offermann G, Ziegler R, Benz G, Lühmann H, Sanchez D, Reutter A, Severin M (1979) Renal bone disorders in children. Therapy with Vitamin D3 or 1,25 dihydroxycholecalciferol. Proc Eur Dial Transplant Assoc 16:644.PubMedGoogle Scholar
  50. Burnett CH, Dent CH, Harper CH, Warland BJ (1964) Vitamin D-resistant rickets: Analysis of twentyfour pedigrees with hereditary and sporadic cases. Am J Med 36:222.PubMedGoogle Scholar
  51. Butler AM, Wilson JL, Faber S (1936) Dehydration and acidosis with calcification at renal tubules. J Pediatr 8:489.Google Scholar
  52. Cadenat H, Combelles R, Fabert G, Clouet M (1977) Calcification du système dentaire sous dialyse. Rev Stomatol Chir Maxillofac 78:491.PubMedGoogle Scholar
  53. Calenoff L, Norfray J (1973) Magnification digital roentgenography: A method for evalution renal osteodystrophy in hemodialyzed patients. Am J Roentgenol 118:282.Google Scholar
  54. Cameron HC (1918) Case of osteomalacia and infantilism with renal deficiency. Proc R Soc Med 2:22.Google Scholar
  55. Catell HS, Levin S, Kopitz S, Lyune ED (1971) Reconstructive surgery in children with azotemic osteodystrophy. J Bone Joint Surg 53:217.Google Scholar
  56. Cavallino R, Grossman H (1968) Wilson’s disease presenting with rickets. Radiology 90:493.PubMedGoogle Scholar
  57. Chambers RA, Pratt RTC (1956) Idiosyncrasy to fructose. Lancet 2:340.Google Scholar
  58. Chan AM, Lynch MJG, Bailey JD, Ezrin C, Fraser D (1970) Hypothyroidism in cystionosis. A clinical, endocrinologic and histologic study involving sixteen patients with cystinosis. Am J Med 48:678.PubMedGoogle Scholar
  59. Chan JCM (1976) Renal osteodystrophy in children. Clin Pediatr (Phila) 15:996.Google Scholar
  60. Chan JCM, Oldham SB, De Luca HF (1977) Effectiveness of 1-hydroxyvitamin D3 in children with renal osteodystrophy associated with hemodialysis. J Pediatr 90:820.PubMedGoogle Scholar
  61. Chan Y-C, Chin CC, Tsou HW (1957) Clinical observations on twenty-five cases of hepatolenticular degeneration. Chin J Neurol Psychiat 3:45.Google Scholar
  62. Chantier C, Donckerwolcke RA, Brunner FP, Bryngerg H, Hathway RA, Jacobs C, Seiwood NH, Wing AJ (1979) Combined report on regular dialysis and transplantation in Europe 1978. Proc Eur Dial Transplant Assoc 16:74.Google Scholar
  63. Chantier S, Holliday MA (1973) Growth in children with renal disease with particular reference to the effects of calorie malnutrition, a review. Clin Nephrol 1:230.Google Scholar
  64. Chesney RW, Mazess RB, Rose PG, Jax DK (1977) Bone mineral status measured by direct photon absorptiometry in childhood renal disease. Pediatrics 60:864.PubMedGoogle Scholar
  65. Chesney RW, Mazess RB, Rose PG, Jax DK, DeLuca HF (1978) Bone mineral status in childhood renal disease. Am J Roentgenol 131:544.Google Scholar
  66. Chesnut CH, Nelp WB, Denney JD, Sherrard DJ (1973) Measurement of total body calcium (bone mass by neutron activation analysis): applicability to bone wasting disease. In: Frame B, Parfitt AM, Duncan H (eds) Clinical aspects of metabolic bone disease. Excerpta Medica, AmsterdamGoogle Scholar
  67. Chevrot A, Pallardy G, Ledoux-Lebard G (1978) Skeletal manifestations of hyperthyroidism. J Radiol Electrol Med Nucl 59:29.Google Scholar
  68. Chisholm JJ Jr, Harrison HC, Eberlein WR (1955) Amino-aciduria hypophosphatemia, and rickets in lead poisoning. Am J Dis Child 89:159.Google Scholar
  69. Chung SMK, Batterman SC, Brighton CT (1976) Shear strength of the human femoral capital epiphyseal plate. J Bone Joint Surg [Am] 58:94.Google Scholar
  70. Coburn JW, Brickmann AS, Sherrard DJ, Singer FR, Wong FGC, Baylink DJ, Norman AW (1978) Renal osteodystrophy and its relation to vitamin D: identification of a mineralising defect unrelated to vitamin D. In: Copp DH, Talmage RV (eds) Endocrinology of calcium metabolism. Excerpta Medica, AmsterdamGoogle Scholar
  71. Coe FL, Firpo JJ (1975) Evidence for mild reversible hyperparathyreoidism in distal renal tubular acidosis. Arch Intern Med 135:1485.PubMedGoogle Scholar
  72. Cooke RE, Boyden DG, Haller E (1960) The relationship of acidosis and growth retardation. J Pediatr 57:326.PubMedGoogle Scholar
  73. Cori GT, Cori CF (1952) Glucose-6-phosphatase of the liver in glycogen storage disease. J Biol Chem 199:661.PubMedGoogle Scholar
  74. Crawford T, Dent CE, Lucas P, Martin NH, Nasim JR (1954) Osteosclerosis associated with chronic renal failure. Lancet 2:981.Google Scholar
  75. Creutzig H, Vick H, Freyschmidt J, Vykoupil K, Bahlmann J (1974) Renale Osteopathie bei terminaler Niereninsuffizienz und Dialysebehandlung. Szintigraphische Untersuchung. In: Nephrologie in Klinik und Praxis, Bd 4, S 185. Dustri, MünchenGoogle Scholar
  76. Creveld S van (1961) Clinical course of glycogen storage disease. Chemi Weekblad 57:445.Google Scholar
  77. Dastur DK, Manghani DK, Wadia NH (1968) Wilson’s disease in India. I. Geographic, genetic and clinical aspects in 16 families. Neurology 18:21.PubMedGoogle Scholar
  78. David DS, Sakai S, Brennan BL, Riggio RR, Cheigh J, Stenzel KH, Rugin AL, Sherwood LM (1973) Hypercalcemia after renal transplantation. Long-term follow up data. N Engl J Med 289:398.PubMedGoogle Scholar
  79. Davies DR, Friedman M (1966) Complications after parathyroidectomy. Fractures from low calcium and magnesium convulsions. J Bone Joint Surv [Br] 48B:117Google Scholar
  80. Debnam JW, Bates ML, Kopelman RC, Teitelbaum SL (1977) Radiological/pathological correlations in uremic bone disease. Radiology 125:653.PubMedGoogle Scholar
  81. Debré R, Marie J, Cleret F, Messimy R (1934) Rachitisme tardif coexistent avec une néphrite chronique et une glycosurie. Arch Méd Ent 37:591Google Scholar
  82. Debré R, Royer P, Lebstradet H, Straub W (1955) L’insuffisance tubulaire congenitale avec arriération mentale, cataracte et glaucome (syndrome de Lowe). Arch Fr Pediatr 12:331.Google Scholar
  83. DeLuca HF (1975) Minireview: regulation of vitamin D metabolism. Life Sci 17:1351.PubMedGoogle Scholar
  84. DeLuca HF (1979) Vitamin D. Metabolism and function. Springer, Berlin Heidelberg New YorkGoogle Scholar
  85. DeLuca R, Guzzetta F (1965) L’ipercalciuria idiopatica infantile. Pediatria (Napoli) 73:613.Google Scholar
  86. Dent CE (1952) Rickets and osteomalacia from renal tubule defects. J Bone Joint Surg [Br] 35:266.Google Scholar
  87. Dent CE (1973) In: Frame B, Parfitt AM, Duncan H. (eds) Clinical aspects of metabolic bone disease. Excerpta Medica, Amsterdam, p 464Google Scholar
  88. Dent CE, Hodson CJ (1954) General softening of bone due to metabolic causes. II. Radiological changes associated with certain metabolic bone disease. Br J Radiol 27:605.PubMedGoogle Scholar
  89. Dent CE, Harris H (1956) Hereditary forms of rickets and osteomalacia. J Bone Joint Surg [Br] 38:204.Google Scholar
  90. Dent CE, Harper Ch M, Philpott GR (1961) The treatment of renal glomerular osteodystrophy. Q J Med 117:1.Google Scholar
  91. Dent CE, Friedman M (1964) Hypercalciuric rickets associated with renal tubular damage. Arch Dis Child 39:240.PubMedGoogle Scholar
  92. Doleczyky SJ, Filipkin MA, Chutoretzky MB, Samoilowitsch EF (1978) Electroroentgenography in the pediatric Medicina, MoskauGoogle Scholar
  93. Drezner MK, Neelon FA, Haussier M, McPherson HT, Lebovitz HE (1976) 1,25-Dihydroxycholecalciferol deficiency: the probable cause of hypocalcemia and metabolic bone disease in pseudohypoparathyroidism. J Clin Endocrinol Metab 42:621.PubMedGoogle Scholar
  94. Drinkard JP, Lee DNB, Gonick HC (1969) Parathormone (PTH) and 47 calcium kinetics changes with alkali treatment of renal tubular acidosis (RTA). In: Proceedings of the Third Annual Meeting of the American Society for Nephrology, p 17Google Scholar
  95. Etches P, Pickering D, Smith R (1977) Cystinotic rickets treated with vitamin D metabolites. Arch Dis Child 52:661.PubMedGoogle Scholar
  96. Fanconi G (1936) Der frühinfantile nephrotisch-glykosurische Zwergwuchs mit hypophosphatämischer Rachitis. Jahrb Kinderheilk 147:299.Google Scholar
  97. Fanconi G (1945) Weitere Beiträge zur Cystinkrankheit. Helv Paediatr Acta 1:183.Google Scholar
  98. Fanconi G, Bickel H (1949) Die chronische Aminoaciduria (Aminosäurendiabetes oder nephrotisch-glukosurischer Zwergwuchs) bei der Glykogenose und der Cystinkrankheit. Helv Paediatr Acta 4:359.PubMedGoogle Scholar
  99. Feist JH (1970) The biologic basis of radiologic findings in bone disease. Recognition and interpretation of abnormal bone architecture. Radiol Clin North Am 8:183.PubMedGoogle Scholar
  100. Feller ER, Schumacher HR (1972) Osteoarticular changes in Wilson’s disease. Arthritis Rheum 15:259.PubMedGoogle Scholar
  101. Felts JH, Whitley JE, Anderson DD, Carpenter HM, Bradshaw HH (1965) Medical and surgical treatment of azotemic osteodystrophy. Ann Intern Med 62:1772.Google Scholar
  102. Feng Y-K (1957) Wilson’s disease. Report of 10 cases. Chin Med J [Engl] 75:631.Google Scholar
  103. Ferran JL, Luciani JC, Meunier P, Dumas R (1977) Ostéodystrophie rénale de l’enfant.’ Confrontations radio-histologiques. J Radiol Electrol Med Nucl 58:173.PubMedGoogle Scholar
  104. Finby N, Beam AG (1958) Roentgenographic abnormalities of the skeletal system in Wilson’s disease (hepatolenticular degeneration). Am J Roentgenol 79:603.Google Scholar
  105. Fine RN, Isaacson AS, Payne V, Grushkin CM (1972) Renal homotransplantation. J Pediatr 80:243PubMedGoogle Scholar
  106. Fischer E (1979) Die Weichteilveränderungen der Finger bei der rheumatischen Polyarthritis. Ergebnisse nach Weichstrahlaufnahmen in 3 Ebenen. Radiologe 19:119.PubMedGoogle Scholar
  107. Floman Y, Yosipovitch Z, Licht A, Viskoper RJ (1975) Bilateral slipped upper femoral epiphysis. A rare manifestation of renal osteodystrophy — case report with discussion of its pathogenesis. Isr J Med Sci 11:15.PubMedGoogle Scholar
  108. Förster R (1887) Über Schrumpfnieren im Kindesalter. Z Kinderheilkd 26:38.Google Scholar
  109. Follis RH Jr (1953) Skeletal changes associated with hyperparathyroidism. Bull Johns Hopkins Hosp 92:405.PubMedGoogle Scholar
  110. Follis RH Jr, Jackson DA (1943) Renal osteomalacia and osteitis fibrosa in adults. Bull Johns Hopkins Hosp 72:232.Google Scholar
  111. Follis RM (1950) Renal rickets and osteitis fibrosa in children and adolescents. Bull Johns Hopkins Hosp 78:593.Google Scholar
  112. Fournier AE, Arnaud CD, Johnson WJ, Tailor WF, Goldsmith RS (1971) Etiology of hyperparathyroidism and bone disease during chronic hemodialysis. II. factors affecting serum immunoreactive parathyroid hormone. J Clin Invest 50:599.PubMedCentralPubMedGoogle Scholar
  113. Fraser DR, Salter RB (1958) The diagnosis and management of the various types of rickets. Pediatr Clin North Am 26:417.Google Scholar
  114. Fraser DR, Kodicek E (1970) Unique biosynthesis by kidney of a biologically active vitamin D metabolite. Nature 228:164.Google Scholar
  115. Froesch ER (1978) Essential fructosuria, hereditary fructose intolerance, and fructose-1-diphosphatase deficiency. In: Stanbury JB, Wyngaarden JB, Frederickson DS (eds) The metabolic basis of inherited disease. McGraw Hill, New York St Louis San FranciscoGoogle Scholar
  116. Froesch ER, Prader A, Labhart A, Stuber HW, Wolf HP (1957) Die hereditäre Fructoseintoleranz, eine bisher nicht bekannte kongenitale Stoffwechselstörung. Schweiz Med Wochenschr 87:1168.PubMedGoogle Scholar
  117. Frost HM (1966) The bone dynamics in osteoporosis and osteomalacia. Charles C Thomas, Springfield, IllGoogle Scholar
  118. Frost HM (1973) Bone remodelling and its relationship to metabolic bone disease. Charles C Thomas, Springfield IllGoogle Scholar
  119. Garabedian M, Tanaka Y, Holick MF, DeLuca HF (1974) Response of intestinal calcium transport and bone calcium mobilization to 1,25-dihydroxyvitamin D3 in thyreoparathyroidectomized rats. Endocrinology 94:1022.PubMedGoogle Scholar
  120. Garner A, Ball J (1966) Quantitative observations on mineralized and unmineralized bone in chronic renal azotemia and intestinal malabsorption syndrome. J Path Bact 91:545.PubMedGoogle Scholar
  121. Garty R, Copper M, Tabachnik E (1974) The Fanconi syndrome associated with hepatic glycogenosis and abnormal metabolism of galactose. J Pediatr 85:821.PubMedGoogle Scholar
  122. Geiger H (1970) Röntgenologische Befunde bei Cystinose. Fortschr Röntgenstr 113:111.Google Scholar
  123. Gentil Cl, Habib R, Le Tan Vinh CJ, Gabilan JC, Courtecuisse V, Alagille D, Lelong M (1962) Nanisme avec rachitisme, hypercalciurie et proteinuric Ann Pediatr 38:165Google Scholar
  124. Gilli G (1975) Therapie der Wachstumsstörungen bei chronischer Niereninsuffizienz. Monatsschr Kinderheilkd 123:112.Google Scholar
  125. Gilmour JR (1947) The parathyroid glands and skeleton in renal disease. Oxford Medical Publications, LondonGoogle Scholar
  126. Ginzler AM, Jaffe HL (1941) Osseous findings in chronic renal insufficiency in adults. Am J Pathol 17:293.PubMedGoogle Scholar
  127. Goldman AB, Lane JM, Salvati E (1978) Slipped capital femoral epiphyses complicating renal osteodystrophy: a report of three cases. Radiology 126:333.PubMedGoogle Scholar
  128. Greenfield GB (1972) Roentgen appearance of bone and soft tissue changes in chronic renal disease. Am J Roentgenol 116:149.Google Scholar
  129. Greulich WW, Pyle SI (1959) Radiographic atlas of skeletal development of the hand and wrist, 2nd edn. Standford University Press, StandfordGoogle Scholar
  130. Griffiths HJ, Zimmermann RE, Lazarus M, Lowrie E, Gottlieb MN, Philips E, Pomerantz K (1977) The long-term follow-up of 195 patients with renal failure: A preliminary report. Radiology 122:643.PubMedGoogle Scholar
  131. Grünebaum M, Lebowitz RL (1977) Hypothyroidism in cystinosis. Am J Roentgenol 129:629.Google Scholar
  132. Hambridge KM, Goodmann SI, Wolravenes PA, Mauer SM, Brettschneider L, Penn I, Storzl TE (1969) Accumulation of cystine following renal homo transplantation for cystinosis. Pediatr Res 3:364.Google Scholar
  133. Hamperl H (1944) Lehrbuch der pathologischen Anatomie. Springer, BerlinGoogle Scholar
  134. Hamperl H, Wallis U (1933) Renale Rachitis und renaler Zwergwuchs. Virchows Arch [Pathol Anat] 288:119.Google Scholar
  135. Hampers CL, Katz AI, Wilson RE, Merrill JP (1969) Calcium metabolism and osteodystrophy after renal transplantation. Arch Int Med 124:282.Google Scholar
  136. Harrison HE (1957) The varieties of rickets and osteomalacia associated with hypophosphatemia. Clin Orthop 9:61.PubMedGoogle Scholar
  137. Harrison HE, Harrison HC (1941) The effects of acidosis upon the renal tubular reabsorption of phosphate. Am J Physiol 134:781.Google Scholar
  138. Harrison HE, Harrison HC (1979) Disorders of calcium and phosphate metabolism in childhood and adolescence. Saunders, PhiladelphiaGoogle Scholar
  139. Haussler MR, Hughes MR, Pike JW, McCain TA (1977) Radiology and receptor assay for 1,25 dihydroxy vitamin D: biochemical, physiologic and clinical applications. In: Schaefer K, Coburn JW, DeLuca HF, Fraser D, Grigoleit HG, Herrath D v (eds) Vit D, biochemical, chemical and clinical aspects. De Gruyter, Berlin, p 473Google Scholar
  140. Hauswaldt C, Wolf G (1974) Zeichen der renalen Osteopathie auf der Thorax-Übersichtsaufnahme. Röfo 120:186.Google Scholar
  141. Heath DA, Martin DJ (1970) Periosteal new bone formation in hyperparathyreoidism associated with renal failure. Br J Radiol 43:515.Google Scholar
  142. Hehrmann R, Tidow G, Offner G, Krohn HP, Hesch RD, Pichelmayer R (1980) Plasma-Parathormon nach Nierentransplantation. Ein empfindlicher Parameter zur Beurteilung der postoperativen Transplantatfunktion. Klin Wochenschr 58:249.PubMedGoogle Scholar
  143. Hermann HJ, Gahl G (1976) Knochenszintigraphie bei der renalen Osteopathie. Nucl Med 15:223.Google Scholar
  144. Hers HG (1964) Glycogen storage disease in advances in metabolic disorders. In: Levin R, Luft R (eds). Academic, New YorkGoogle Scholar
  145. Heuck F, Babo H v (1974) Röntgenbefunde bei primärem Hyperparathyreoidismus. Radiologe 14:206.PubMedGoogle Scholar
  146. Holick MF, Schnoes HK, DeLuca HF (1971a) Identification of 1,25-dihydroxycholecalciferol, a form of vitamin D3 metabolically active in the intestine. Proc Natl Acad Sci USA 68:803PubMedGoogle Scholar
  147. Holick MF, Schnoes HK, DeLuca HF, Gray RW, Boyle IT, Suda T (1972) Isolation and identification of 24,25-dihydroxychole-calciferol: a metabolite of vitamin D3 made in the kidney. Biochemistry 11:4251.PubMedGoogle Scholar
  148. Holliday UA (1978) Metabolism and growth in children with kidney insufficiency. Kidney Int 14:299.PubMedGoogle Scholar
  149. Hoshua GE (1973) Hepatolenticular degeneration (Wilson’s disease) and rickets in children. Indian J Med Res 61:1876.Google Scholar
  150. Huguenin M, Schacht R, David R (1974) Infantile rickets with severe proximal renal tubular acidosis, responsive to vitamin D. Arch Dis Child 49:955.PubMedGoogle Scholar
  151. Huth EJ, Webster GD, Elkinton JR (1960) The renal excretion of hydrogen ion in renal tubular acidosis. III. An attempt to detect latent cases in a family; comments on nosology, genetics and etiology of the primary disease. Am J Med 29:586.Google Scholar
  152. Illig G, Prader A (1961) Primäre Tubulopathien: II. Ein Fall von idiopathischem Gluko-Amino-Phosphat-Diabetes (De Toni-Debre-Fanconi Syndrom). Helv Paediatr Acta 16:622.Google Scholar
  153. Imhäuser S (1961) Therapie der Epiphysenlösung unter Zugrundelegung ihrer Pathogenese. Verh Dtsch Orthop Ges 49:241.Google Scholar
  154. Jensen PS, Klinger AS (1977) Early radiographic manifestations of secondary hyperparathyreoidism associated with chronic renal disease. Radiology 125:645.PubMedGoogle Scholar
  155. Jeune M, Gilly R, Hermier M, Frederich A, Collombel C, Raveau J (1967) L’hypercalciurie idiopathique de l’enfant. Pediatrie 22:17.PubMedGoogle Scholar
  156. Kaye M, Pritchard JE, Halpenny GW, Light W (1964) Bone disease in chronic renal failure with particular reference to osteosclerosis. Medicine (Baltimore) 39:151.Google Scholar
  157. Kirkwood JR, Ozonoff MB, Steinbach HL (1972) Epiphyseal displacement after metaphyseal fracture in renal osteodystrophy. Am J Roentgenol 115:547.Google Scholar
  158. Klein A, Joplin RJ, Reidy JA, Hanelin J (1951) Roentgenographic features of slipped capital femoral epiphyses. Am J Roentgenol 66:361.Google Scholar
  159. Krempien B, Ritz E, Beck U, Keilbach H (1972) Micromorphometric and microradiographic studies with correlations to serum parathyroid hormone and calcitonin levels. Virchows Arch [Pathol Anat] 357:251.Google Scholar
  160. Krempien B, Mehls O, Ritz E (1974) Morphological studies on pathogenesis of epiphyseal slipping in uremic children. Virchows Arch [Pathol Anat] 362:129.Google Scholar
  161. Krempien B, Ritz E, Mehls O, Herrath D v (1977) Experimentelle und pathologisch-anatomische Untersuchungen zur urämischen Wachstumsstörung. In: Schulz W, Gessler U, Delling G (eds) Knochenveränderungen bei Niereninsuffizienz. Dustri, MünchenGoogle Scholar
  162. Kunze WP (1976) Nephropathische Cystinose, Hyper-parathyreoidismus und Kalkmetastasen. Dtsch Med Wochenschr 101:545.PubMedGoogle Scholar
  163. Kyle LH, Merony MH, Freemann HE (1954) Study of the mechanism of bone disease in hypophosphatemic glycosuric osteomalacia. J Clin Endocrinol Metab 14:365.PubMedGoogle Scholar
  164. Lacroix P, Verbrugge J (1951) Slipping of the upper femoral epiphyses. J Bone Joint Surg [Am] 22:371.Google Scholar
  165. La Du BN, Gjessing LR (1978) Tyrosinosis and tyrosinemia. In: Stanbury JB, Wyngaarden JB, Frederickson DS (eds) The metabolic basis of inherited disease. McGraw Hill, New YorkGoogle Scholar
  166. Lalli AF, Lapides J (1963) Osteosclerosis occuring in renal disease. Am J Roentgenol 93:924.Google Scholar
  167. Lampert F, Mayer H (1967) Glykogenose der Leber mit Galaktoseverwertungsstörung und schwerem Fanconi-Syndrom. Z Kinderheilkd 98:133.PubMedGoogle Scholar
  168. Lampert F, Mayer H, Tocci PM, Nyhan WL (1967) Fanconi Syndrome in glycogen storage disease. In: Nyhan WL (ed) Amino acid metabolism and genetic variation. McGraw Hill, New YorkGoogle Scholar
  169. Larkins RG, McAuley SJ, Mclntyre I (1975) Inhibitors of protein and RNA synthesis and 1,25-dihydroxy-cholecalciferol formation in vitro. Mol Cell Endocrinol 2:193.PubMedGoogle Scholar
  170. Larochelle J, Mortezai A, Bélanger M, Trembleay M, Claveau JC, Aubin G (1967) Experience with 37 infants with tyrosinemia. Can Med Assoc J 97:1051.PubMedCentralPubMedGoogle Scholar
  171. Lawson RK, Talwalkar YB, Hodges CV (1975) Renal transplantation in cystinosis. J Urol 113:552.PubMedGoogle Scholar
  172. Leaf A (1966) The syndrome of osteomalacia, renal glycosuria, aminoaciduria and increased phosphate clearance (the Fanconi syndrome). In: Stanbury JB, Wyngaarden JB, Frederickson DS (eds) The metabolic basis of inherited disease. McGraw Hill Book, New YorkGoogle Scholar
  173. Lefebvre G, Biserte G, Woillez M, Traisnel M, Gosselin J, Combaud A (1957) Étude clinique, génétique et biologique du syndrome de Lowe-Bickel. Pediatrie 12:527.Google Scholar
  174. Lefke M, Siebert HG, Friedmann G (1971) Röntgenologische Veränderungen bei Calciumstoffwechselstörungen im Terminalstadium der Niereninsuffizienz. Dtsch Med Wochenschr 96:283.Google Scholar
  175. Le Geros RZ, Contiguglia SR, Alfrey AC (1973) Evidence for two types of calcium phosphate deposits in uremia. Calcif Tissue Res 13:113.Google Scholar
  176. Lelong M, Alagille D, Gentil C, Colin J, Tupin J, Bouguier J (1962) Cirrhose hépatique et tubulopathie par absence congenitale de l’aldolase hépatique: intolérance héréditaire au fructose. Bull Soc Méd Hôp (Paris) 113:58.Google Scholar
  177. Lemann J Jr, Litzow JR, Lennon EJ (1966) The effects of chronic acid loads in normal man; further evidence for the participation of bone mineral in the defense against chronic metabolic acidosis. J Clin Invest 45:1608.PubMedCentralPubMedGoogle Scholar
  178. Letteri JM, Ellis KJ, Orofino DP, Ruggieri S, Asad SN, Cohn SH (1974) Altered calcium metabolism in chronic renal failure. Kidney Int 6:45.PubMedGoogle Scholar
  179. Letteri JM, Cohn SH (1977) Total body neutron activation analysis in the study of mineral homeostasis in chronic renal disease. In: David DS (ed) Calcium metabolism in renal failure and nephrolithiasis. Wiley & Sons, New YorkGoogle Scholar
  180. Levine E, Erken EH, Price HI, Meyers AM, Solomon L (1977) Osteonecrosis following renal transplantation. Am J Roentgenol 128:985.Google Scholar
  181. Lewy JE, New MI (1978) Growth in children with renal failure. Am J Med 58:65.Google Scholar
  182. Lightwood R (1935) Calcium infarction of the kidneys in infants. Arch Dis Child 10:205.Google Scholar
  183. Lightwood R, McLagan NF, Williams JG (1936) Persistent acidosis in an infant. Cause not yet ascertained. Proc R Soc Med 29:1431.PubMedCentralPubMedGoogle Scholar
  184. Lightwood R, Payne WW, Black JA (1953) Infantil renal acidosis. Pediatrics 12:628.PubMedGoogle Scholar
  185. Lindsay RM, Boyle JT, Luke RG, Kennedy AC (1968) The endocrine status of regular dialysis patient. Proc Eur Dial Transplant Assoc 5:230.Google Scholar
  186. Lireman DS, Price JDE, Lavener RW, Müller HS (1968) Renal osteodystrophy during hemodialysis for chronic renal failure. Can Med Assoc J 99:668.Google Scholar
  187. Liu SH, Chu HI (1943) Studies of calcium and phosphorous metabolism with special reference to pathogenesis and effect of dihydrotachysterol (At 10) and iron. Medicine (Baltimore) 22:103.Google Scholar
  188. Lomnitz E, Sepulveda L, Stevenson C, Barzalatto J (1966) Primary hyperparathyroidism stimulating rickets. J Clin Endocrinol Metab 26:309.PubMedGoogle Scholar
  189. Looser E (1920) Über pathologische Formen von Infraktionen und Callusbildungen bei Rachitis und Osteomalazie und anderen Knochenerkrankungen. Zentralbl Chir 47:1470.Google Scholar
  190. Looser R (1944) Ein Fall von Cystinspeicherung mit renalem Zwergwuchs und Rachitis. Ann Paediatr 163:251.Google Scholar
  191. Lowe CU, Terrey M, McLachlan EA (1952) Organic aciduria, decreased renal ammonia production, hydrophthalmos and mental retardation. Am J Dis Child 83:165.Google Scholar
  192. Lucas RC (1883) On a form of late rickets associated with albuminuria, rickets of adolescents. Lancet 1:993.Google Scholar
  193. Lucas ZJ, Kempson RL, Palmer J, Korn D, Cohn RB (1969) Renal allotransplantation in man. II. Transplantation in cystinosis, a metabolic disease. Am J Surg 118:159.Google Scholar
  194. Mahoney CP, Striker GE, Hickman RO, Manning GB, Marchioro ThL (1970) Renal transplantation for childhood cystinosis. N Engl J Med 283:397.PubMedGoogle Scholar
  195. Malekzadeh MH, Neustein HB, Schneider JA, Pennisi AJ, Ettenger RB, Uittenbogaart ChH, Kogut MD, Fine RN (1977) Cadaver renal transplantation in children with cystinosis. Am J Med 63:525.PubMedGoogle Scholar
  196. Malekzadeh MH, Ettenger RB, Pennisi AJ, Warshaw BL, Uittenbogaart CH, Fine RN (1979) Treatment of renal osteodystrophy in children with 1.25(OH)2 D3. Proceedings of the Fourth Workshop on Vit D, Berlin (abstract)Google Scholar
  197. Malluche HH, Ritz E, Hodgsen M, Kutschera J, Krause G, Seiffert U, Gatti A, Lange HP (1974) Skeletal lesions and calcium metabolism in early renal failure. Proc Eur Dial Transplant Assoc 11:443.Google Scholar
  198. Malluche HH, Ritz E, Kutschera J, Krause G, Werner E, Gatti A, Seiffert U, Lange HP (1975) Calcium metabolism and impaired mineralisation in various stages of renal insufficiency. In: Norman AW, Schaefer K, Grigoeit HG, Herrath D v, Ritz E (eds) Vitamin D and problems related to uremic bone disease, de Gruyter, BerlinGoogle Scholar
  199. Malluche HH, Ritz E, Lange HP, Kutschera J, Hodgsen M, Seiffert U, Schoeppe W (1976) Bone histology in incipient and advanced renal failure. Kidney Int 9:355.PubMedGoogle Scholar
  200. Malluche HH, Werner E, Ritz E (1978) Intestinal absorption of Ca in incipient and advanced renal failure. Min Electrol Metab 1:263.Google Scholar
  201. Mankin HJ (1974a) Rickets, osteomalacia and renal osteodystrophy, part I. J Bone Joint Surg [Am] 56:101Google Scholar
  202. Mankin HJ (1974b) Rickets, osteomalacia and renal osteodystrophy, part II. J Bone Joint Surg [Am] 56:352Google Scholar
  203. Margolis A (1966) Idiopathic hypercalciuria in children. Pediatr Pol 41:823.PubMedGoogle Scholar
  204. Martin D, DeLuca HF (1969) Calcium transport and the role of vitamin D. Arch Biochem Biophys 134:139.PubMedGoogle Scholar
  205. Maschio G, Bonucci E, Mioni G, DiAngelo A, Ossi E, Valvo E, Lupo A (1974) Biochemical and morphological aspects of bone tissue in chronic renal failure. Nephron 12:437.PubMedGoogle Scholar
  206. Massry SG, Stein R, Garty J, Arieff AJ, Coburn JW, Norman AW (1975) The role of 1.25-dihydroxycholecalciferol in the skeletal resistance to the calcémic actions of parathyroid hormone in uremia. In: Norman AW (ed) Vitamin D and problems related to uremic bone disease. De Gruyter, BerlinGoogle Scholar
  207. Massry SG, Ritz E, Verberckmoes R (1977) Role of phosphate in the genesis of secondary hyperparathyroidism of renal failure. Nephron 18:77.PubMedGoogle Scholar
  208. McCollum EV, Simmonds N, Becker JE, Shipley PG (1922) Studies on experimental rickets. XXI. An experimental demonstration of the existence of a vitamin which promotes calcium deposition. J Biol Chem 53:293.Google Scholar
  209. Mclnnes RR, Shih VE, Erbe RW (1976) Metabolic abnormalities in Lowe syndrome fibroblasts. Pediatr Res 10:368.Google Scholar
  210. McLachan MSF, Wallace M, Senefiratne G (1968) Pulmonary calcification in renal failure. Report of three cases. Br J Radiol 41:99.Google Scholar
  211. McSherry E, Sebastian A, Morris RC Jr (1973) Correction of impaired growth in children with classic renal tubular acidosis by sustained correction of the acidosis. Clin Res 21:700.Google Scholar
  212. McSherry E, Morris RC Jr (1978) Attainment and maintenance of normal stature with alkali therapy in infants and children with classic renal tubular acidosis. J Clin Invest 61:509.PubMedCentralPubMedGoogle Scholar
  213. Medes G (1932) A new error of tyrosine metabolism: tyrosinosis. The intermediary metabolism of tyrosine and phenylalanine. Biochem J 26:911.Google Scholar
  214. Medes G (1966) Tyrosinosis. In: Gjessing LR (ed) Symposium on Tyrosinosis. In Honour of Dr. Medes G, 2.–3. June 1965. Universitetsforlaget, OsloGoogle Scholar
  215. Meema HE (1973) The combined use of morphometric and microradioscopic methods in the diagnosis of metabolic bone disease. Radiolog 13:111.Google Scholar
  216. Meema HE, Schatz DL (1970) Simple radiologic demonstration of cortical bone loss in thyreotoxicosis. Radiology 97:9.PubMedGoogle Scholar
  217. Meema HE, Rabinovich S, Meema S, Lloyd GJ, Oreopoulos DG (1972) Improved radiological diagnosis of azotemic osteodystrophy. Radiology 102:1.PubMedGoogle Scholar
  218. Meema HE, Meema S (1973) Microradioscopic bone structure of the hand in thyreotoxicosis, renal osteodystrophy and acromegaly. In: Frame B, Parfitt AM, Duncan H (eds) Clinical aspects of metabolic bone disease. Excerpta Medica, AmsterdamGoogle Scholar
  219. Meema HE, Oreopoulos DG, Rabinovich S, Husdan H, Rapoport H (1974) Periostal new bone formation (periosteal neostosis) in renal osteodystrophy. Radiology 110:513.PubMedGoogle Scholar
  220. Meema HE, Harrison JE, McNeill KG, Oreopoulos DG (1977) Correlations between peripheral and central skeletal mineral content in chronic renal failure patients and in osteoporotics. Radiology 1:169.Google Scholar
  221. Mehls O (1975) Therapie der urämischen Osteopathie. Monatsschr Kinderheilkd 123:174.Google Scholar
  222. Mehls O, Ritz E, Krempien B, Willich E, Bommer J, Schärer K (1973a) Roentgenological signs in the skeleton of uremic children. An analysis on the anatomical principle underlying the roentgenological changes. Pediatr Radiol 1:183PubMedGoogle Scholar
  223. Mehls O, Krempien B, Ritz E, Schärer K, Schüler HW (1973b) Renal osteodystrophy in children on maintenance hemodialysis. Proc Eur Dial Transplant Assoc 10:197PubMedGoogle Scholar
  224. Mehls O, Ritz E, Krempien B, Gilli G, Link K, Willich E, Schärer K (1975a) Slipped epiphyses in renal osteodystrophy. Arch Dis Child 50:545PubMedGoogle Scholar
  225. Mehls O, Ritz E, Krempien B, Gilli G, Schärer K (1975b) Slipped epiphyses in renal osteodystrophy. In: Norman AW (ed) Vitamin D and problems related to uremic bone disease. De Gruyter, BerlinGoogle Scholar
  226. Mehls O, Ritz E, Parsch K, Gilli G, Schärer K, Bommer J (1976a) Therapeutische Erfahrungen bei urämischer Epiphysenlösung. Klin Wochenschr 54:405PubMedGoogle Scholar
  227. Mehls O, Broyer M, Wesch H (1976b) Quantitative Mineralsalzmessung des kindlichen urämischen Skeletts mit Hilfe der Photonabsorptionsdensitometrie. Couvoisiere B, Donath A (eds). Editions Médicine et Hygiene, Genf, p 7Google Scholar
  228. Mehls O, Ritz E, Gilli G, Kreusser W (1978a) Growth in renal failure. Nephron 21:237PubMedGoogle Scholar
  229. Mehls O, Ritz E, Gilli G, Wangdak T, Krempien B (1978b) Effect of vitamin D on growth in experimental uremia. Am J Clin Nutr 31:1921Google Scholar
  230. Mehls O, Ritz E, Kreusser W, Krempien B (1980) Renal osteodystrophy in uremic children. In: Clinics in endocrinology and metabolism, vol 9. Saunders, London, p 151Google Scholar
  231. Mehls O, Ritz E, Oppermann HC, Guignard IP (1981) Femural head necrosis in uremic children without steroid treatment and transplantation. J. Ped 99:926–929.Google Scholar
  232. Milhaud G (1964) Téchnique nouvelle de mise en évidence d’erreurs congénitales en métabolism chez l’homme. Argent Bras Endocr 13:49.Google Scholar
  233. Mindelzun R, Elkin M, Scheinberg IH, Sternlieb I (1970) Skeletal changes in Wilson’s disease; a radiological study. Radiology 94:127.PubMedGoogle Scholar
  234. Moll H, Schmid F (1958) Radiologische Grundzüge der atypischen Rachitisformen. Z Kinderheilkd 80:469.PubMedGoogle Scholar
  235. Moorehead JF, Wills MR, Ahmed K, Baillod RA, Varghese Z, Tatler GLV (1974) Hypophosphataemic osteomalacia after cadaveric renal transplantation. Lancet 1:694.Google Scholar
  236. Morgan HG, Stewart WK, Lowe KG, Stowers JM, Johnstone JH (1962) Wilson’s disease and the Fanconi syndrome. QJ Med NS 31:361.Google Scholar
  237. Morris RC Jr (1968a) An experimental renal acidification defect in patients with hereditary fructose intolerance. I. Its resemblance to renal tubular acidosis. J Clin Invest 47:1389PubMedCentralPubMedGoogle Scholar
  238. Morris RC Jr (1968b) An experimental renal acidification defect in patients with hereditary fructose intolerance. II. Its distinction from classical renal tubular acidosis: its resemblance to the renal acidification defect associated with the Fanconi syndrome of children with cystinosis. J Clin Invest 47:1648PubMedCentralPubMedGoogle Scholar
  239. Nordin BEC (1973) Osteoporosis. J Clin Endocrinol Metab 2:155.Google Scholar
  240. Nordmann Y, Shapira F, Dreyfus JC (1968) A structurally modified liver aldolase in fructose intolerance: immunological and kinetic evidence. Biochem Biophys Res Commun 31:884.PubMedGoogle Scholar
  241. Norfray J, Calenoff L, Del Greco F, Krumlovsky FA (1975) Renal osteodystrophy in patients on hemodialysis as reflected in the bony pelvis. Am J Roentgenol 125:352.Google Scholar
  242. Nützenadel W, Lutz P, Bickel H (1972) Tyrosinose: primäre und sekundäre biochemische Veränderungen. Z Kinderheilkd 113:193.PubMedGoogle Scholar
  243. Odievre M (1966) Glycogénose hépato-rénale avec tubulopathie complex. Rev Int Hepatol 16:1.PubMedGoogle Scholar
  244. Parfitt AM (1969) Soft-tissue calcification in uremia. Arch Intern Med 124:544.PubMedGoogle Scholar
  245. Parfitt AM (1972) Renal osteodystrophy. Orthop Clin North Am 3:681.PubMedGoogle Scholar
  246. Parfitt AM (1976a) The actions of parathyroid hormone on bone: Relation to bone remodeling and turnover, calcium homeostasis, and metabolic bone disease. Part IV and IV parts: The state of the bones in uremic hyper-parathyroidism — the mechanisms of skeletal resistance to PTH in renal failure and pseudohypoparathyroidism and the role of PTH in osteoporosis, osteopetrosis and osteofluorosis. Metabolism 25:1157PubMedGoogle Scholar
  247. Parfitt AM (1976b) The action of parathyroid hormone on bone. Part III of IV parts: PTH and osteoblasts, the relationship between turnover and bone loss, and the state of bones in primary hyperparathyroidism. Metabolism 25:1033PubMedGoogle Scholar
  248. Parfitt AM (1977) Clinical and radiographic manifestations of renal osteodystrophy. In: David DS (ed) Calcium and metabolism in renal failure and nephrolithiasis. John Wiley & Sons, New York, pp 145Google Scholar
  249. Park EA (1939) Observations on the pathology of rickets with particular reference to the changes at the cartilage shaft junctions of the growing bones. Bull NY Acad Med 15:495.Google Scholar
  250. Parsons LG (1927) The bone changes occuring in renal and coeliac infantilism and their relationship to rickets. I. Renal rickets. Arch Dis Child 2:1.PubMedGoogle Scholar
  251. Patrick AD, Lake BD (1968) Cystinosis: Electron-microscopic evidence of lysosomal storage of cystine in lymph-node. J Clin Pathol 21:571.PubMedGoogle Scholar
  252. Peter-Baron U, Mehls O, Komposch G (1980) Strukturveränderungen der Hartsubstanzen im dentoalveolären Bereich bei Kindern mit Niereninsuffizienz. Fortschr Kieferorthop 41:594–601.Google Scholar
  253. Peters PE, Osmers F, Müller H, Loew H (1977) Möglichkeiten der Früherkennung der renalen Osteopathie mit Hilfe der Xeroradiographie der Hände. In: Schulz W, Gessler U, Dalling G (Hrsg) Nephrologie in Klinik und Praxis, Bd 4. Dustri, MünchenGoogle Scholar
  254. Pierides AM, Ellis HA, Peart KM, Simpson W, Uldall PR, Kerr DNS (1975) Assessment of renal osteodystrophy following renal transplantation. Proc Eur Dial Transplant Assoc 11:481.PubMedGoogle Scholar
  255. Placios E (1967) Hereditary osteo-onychodysplasia: The nail-patelle syndrome. Am J Roentgenol 101:842.Google Scholar
  256. Ponchon G, De Luca HF (1969) The role of the liver in the metabolism of vitamin D. J Clin Invest 48:1213.Google Scholar
  257. Ponseti IV, McClintock R (1956) The pathology of slipping of the upper femoral epiphyses. J Bone Joint Surg [Am] 38:11.Google Scholar
  258. Prader A, Illig R, Heierli E (1961) Eine besondere Form der primären Vitamin D-resistenten Rachitis mit Hypocalciämie und autosomal dominantem Erbgang. Helv Paediatr Acta: 452Google Scholar
  259. Prager PJ, Krause KH, Ritz E, Schmidt-Gayk H (1977a) Handskelettaufnahmen in Mammographietechnik bei Patienten unter antiepileptischer Medikation. Röfo 126:371PubMedGoogle Scholar
  260. Prager PJ, Ritz E, Bommer J, Krempien B, Malluche HH, Schnurr H (1977b) Wert und Grenzen der Röntgenskelettdiagnostik bei renaler Osteopathie; histologisch-röntgenologische Vergleichsuntersuchungen. In: Schulz W, Gessler U, Delling G (Hrsg) Knochenveränderungen bei Niereninsuffizienz. Dustri, MünchenGoogle Scholar
  261. Prager P, Singer R, Ritz E, Krempien B (1978) Diagnostischer Stellenwert der Lamina dura dentium beim sekundären Hyperparathyreoidismus. Röfo 129:2,237Google Scholar
  262. Prive L (1967) Pathological findings in patients with tyrosinemia. Can Med Assoc J 97:1054.PubMedCentralPubMedGoogle Scholar
  263. Pugh GD (1951) Subperiostal resorption of bone: A roentgenographic manifestation of primary hyperparathyroidism and renal osteodystrophy. Am J Roentgenol 66:511.Google Scholar
  264. Rasmussen H, Bordier P (1974) Physiological and cellular basis of metabolic bone disease. Williams & Wilkins, BaltimoreGoogle Scholar
  265. Rayasuria K, Peiris OA, Ratnaike UT, Fonseka CP (1964) Parathyroid adenomas in childhood. Am J Dis Child 107:442.Google Scholar
  266. Reiss E, Canterbury JM, Bilinsky RF (1964) Measurement of parathyroid hormone in renal failure: Etiology and toxic manifestation. Ann Int Med 61:13.Google Scholar
  267. Reiss E, Canterbury JM, Kanter A (1969) Circulating parathyroid hormone concentration in chronic renal insufficiency. Arch Int Med 124:411.Google Scholar
  268. Reiss E, Canterbury JM, Bercovitz MA, Kaplan EL (1970) The role of phosphate in the secretion of parathyroid hormone in man. J Clin Invest 49:2146.PubMedCentralPubMedGoogle Scholar
  269. Resnick D, Niwayama G (1976) Subchondral resorption on bone in renal osteodystrophy. Radiology 118:315.PubMedGoogle Scholar
  270. Richards P, Wrong OM (1972) Dominant inheritance in a family with familial renal tubular acidosis. Lancet 2:998.PubMedGoogle Scholar
  271. Ritz E, Krempien B, Mehls O, Malluche HH (1973) Skeletal abnormalities in chronic renal insufficiency and under maintenance hemodialysis (anatomical analysis). Kidney Int 4:116.PubMedGoogle Scholar
  272. Ritz E, Malluche H, Bommer J, Mehls O, Krempien B (1974) Metabolic bone disease in patients on maintenance haemodialysis. Nephron 12:393.PubMedGoogle Scholar
  273. Ritz E, Prager P, Krempien B, Bommer J (1975) Röntgenologische Veränderungen des Skeletts bei Urämie. Nier Hochdruckkrankh 4:109.Google Scholar
  274. Ritz E, Malluche HH, Krempien B, Mehls O (1977a) Bone histology in renal insufficiency. In: David DS (ed) Calcium metabolism in renal failure and nephrolithiasis. John Wiley & Sons, New York, p 197Google Scholar
  275. Ritz E, Mehls O, Bommer J, Schmidt-Gayk H, Fiegel P, Reitinger H (1977b) Vascular calcifications under maintenance hemodialysis. Klin Wochenschr 55:375PubMedGoogle Scholar
  276. Ritz E, Mehls O, Krempien B, Gilli G, Udes H, Harendza W (1977c) Skeletal growth in uremia. In: Massry SG, Ritz E (eds) Phosphate metabolism. Plenum Press, New YorkGoogle Scholar
  277. Ritz E, Prager P, Krempien B, Bommer J, Malluche HH, Schmidt-Gayk H (1978) Skeletal X-ray findings and bone histology in patients on hemodialysis. Kidney Int 13:316.PubMedGoogle Scholar
  278. Robins DG, French TA, Chakera TMH (1976) Juvenile nephronophthisis associated with skeletal abnormalities and hepatic fibrosis. Arch Dis Child 51:799.PubMedGoogle Scholar
  279. Rodriguez-Soriano J (1971) The renal regulation of acidbase balance and the disturbances noted in renal tubular acidosis. Pediatr Clin North Am 18:529.PubMedGoogle Scholar
  280. Rodriguez-Soriano J, Boichis H, Stark H, Edelmann CM Jr (1967) Proximal renal tubular acidosis: A defect in bicarbonate reabsorption with normal urinary acidification. Pediatr Res 1:81.PubMedGoogle Scholar
  281. Rose GA (1964) The radiological diagnosis of osteoporosis, osteomalacia and hyperparathyroidism. Clin Radiol 15:75.PubMedGoogle Scholar
  282. Rosenoer VM (1961) Bone changes in Wilson’s disease. In: Walshe JM, Cumings JN (eds) Wilson’s disease. Some current concepts. Blackwell, Oxford, p 245Google Scholar
  283. Rosenoer VM, Mitchell RC (1959) Skeletal changes in Wilson’s disease (hepatolenticular degeneration). Brit J Radiol 32:805.PubMedGoogle Scholar
  284. Rotthauwe HW, Fichsel H, Heldt HW, Kirsten E, Reim M, Schmidt E, Schmidt FW, Weseman W (1963) Glykogenose der Leber mit Aminoacidurie und Glukosurie. Klin Wochenschr 41:818.PubMedGoogle Scholar
  285. Royer P, Lestradet H, Nordmann R, Mathieu H, Rodriguez-Soriano J (1962a) Etudes sur quatre cas d’acidose tubulaire chronique idiopathique avec hypocitraturie. Sem Hop Paris (Ann Pediatr) 38:808Google Scholar
  286. Royer P, Mathieu H, Gerbeaux S, Frederich A, Rodriguez-Soriano J, Dartois AM, Cuisinier P (1962b) L’hypercalciurie idiopathique avec nanisme et atteinte renale chez l’enfant. Ann Pediatr 38:147Google Scholar
  287. Rubin P (1969) Dynamic classification of bone dysplasia. New Book Medical Publishers, ChicagoGoogle Scholar
  288. Saenger P, Wiedemann W, Schwartz E, Korth-Schmitz S, Lewy JE, Riggio RR, Rubin AL, Stenzel KH, New MI (1974) Somatomedin and growth after renal transplantation. Pediatr Res 8:163.PubMedGoogle Scholar
  289. Sass-Kortsak A (1965) Copper metabolism. Adv Clin Chem 8:1.PubMedGoogle Scholar
  290. Sass-Kortsak A, Beam AG (1978) Hereditary disorders of copper metabolism. In: Standbury JB, Wyngaarden JB, Frederickson DS (eds) The metabolic basis of inherited disease. McGraw Hill, New YorkGoogle Scholar
  291. Schärer K, Chantier C, Brunner FP, Gurland HJ, Jacobs C, Seiwood NH, Spies G, Wing AJ (1976) Combined report on regular dialysis and transplantation of children in Europe, 1975. Proc Eur Dial Transplant Assoc 13:59.Google Scholar
  292. Schneider AJ, Schulman JD, Seegmiller JE (1978) Cystinosis and the Fanconi syndrome. In: Stanbury JB, Wyngaarden AB, Frederickson DS (eds) The metabolic basis of inherited disease. McGraw Hill, New York St Louis San Francisco, p 1660Google Scholar
  293. Schulman JD, Bradley KH, Seegmiller JE (1969) Cystine: Compartmentalization within lysosomes in cystinotic leucocytes. Science 166:1152.PubMedGoogle Scholar
  294. Schulman JD, Wong V, Olson WH, Seegmiller JE (1970) Lysosomal spite of crystalline deposits in cystinosis as shown by ferritin uptake. Arch Pathol 90:259.PubMedGoogle Scholar
  295. Schulman JD, Bradley KH (1970a) Cystinosis: Selective induction of vacuolation in fibroblasts by L-cysteine-D-penicillamine disulfide. Science 169:595PubMedGoogle Scholar
  296. Schulman JD, Bradley KH (1970b) Metabolism of aminoacids, peptides, and disulfides in the lysosomes of fibroblasts cultured from normal individuals and those with cystinosis. J Exp Med 132:1090PubMedCentralPubMedGoogle Scholar
  297. Schulz A, Delling G (1973) Bone disease in two cases of cystinosis. Histomorphometric analysis of the Vitamin D effect. Beitr Pathol 150:43.PubMedGoogle Scholar
  298. Schwartz EE, Lantieri R, Teplick JG (1977) Erosion of the inferior aspect of the clavicle in secondary hyperparathyreoidism. Am J Roentgenol 129:291.Google Scholar
  299. Scriver CR, Silverberg M, Clow CL (1967) Hereditary tyrosinemia and tyrosyluria. Clinical report on four patients. Can Med Assoc J 97:1047.PubMedCentralPubMedGoogle Scholar
  300. Seegmiller JE (1973) Cystinosis in lysosomes and storage diseases. Hers HG, Hoof V van (eds). Academicum, New YorkGoogle Scholar
  301. Seidin DW, Wilson JD (1978) Renal tubular acidosis. In: Stanbury JB, Wyngaarden JB, Frederickson DS (eds) The metabolic basis of inherited disease, 4th edn. McGraw Hill, New YorkGoogle Scholar
  302. Shapira F, Nordmann Y, Dreyfus JC (1968) La Lésion biochimique de l’intolérance héréditaire au fructose. Détection immunologique d’une aldolase modifiée. Rev Fr Etud Clin Biol 13:261.Google Scholar
  303. Shea D, Mankin HJ (1966) Slipped capital femoral epiphyses in renal rickets. J Bone Joint Surg [Am] 48:349.Google Scholar
  304. Sidbury JB (1965) The genetics of the glycogen storage diseases. Prog Med Genet 4:31.Google Scholar
  305. Silverman FN, Currarino G (1960) Roentgen Manifestation of Hereditary Metabolic Disease in Childhood. Metabolism 9:248.PubMedGoogle Scholar
  306. Simpsin W, Ellis HA, Kerr DNS, McElroy M, McNay RA, Peart KN (1976) Bone disease in long-term hemodialysis: the association of radiological with histological abnormalities. Br. J Radiol 49:105.Google Scholar
  307. Slatopolsky E, Bricker NS (1973) The role of phosphorus restriction in the prevention of secondary hyperparathyreoidism in chronic renal disease. Kidney Int 4:141.PubMedGoogle Scholar
  308. Slatopolsky E, Hruska K, Rutherford WE (1975) Current concepts of parathyroid hormone and Vitamin D metabolism: perturbations in chronic renal disease. Kidney Int [Suppl] 2:90.Google Scholar
  309. Slovis TL, Chand N, Shanovas TO, Fleischmann LE, Brough AJ (1977) Pulmonary calcification in a child with renal failure. Pediatr Radiol 6:112.PubMedGoogle Scholar
  310. Smith FW, Junor BJR (1977) Xeroradiography of the hand in patients with renal osteodystrophy. Br J Radiol 50:261.PubMedGoogle Scholar
  311. Smith JC, Stanton A (1963) Nodular pulmonary calcification in renal failure. Am Rev Respir Dis 100:123.Google Scholar
  312. Sobbe A, Siedek M, Sodomann CP, Düx A (1969) Metastatic calcification in chronic hemodialysis. Röfo 110:851.Google Scholar
  313. Soret R, Dalous A, Fabre J, Rochiccioli P, Ghisoli J, Fabre MTh (1970) Hypercalciurie idiopathique avec nanisme. Arch Fr Pediatr 27:161.Google Scholar
  314. Soriano JR (1978) Renal tubular acidosis. In: Edelmann CH (ed) Pediatric kidney disease, vol II. Little Brown, BostonGoogle Scholar
  315. Soriano JR, Houston IB, Boichis H (1968) Calcium and phosphorus metabolism in the Fanconi syndrome. J Clin Endocrinol Metab 28:1555.Google Scholar
  316. Stanbury JB, Wyngaarden JB, Frederickson DS (1978) The metabolic basis of inherited disease. McGraw Hill, New YorkGoogle Scholar
  317. Stanbury SW (1967) Bony complications of renal disease. In: Black DAK (ed) Renal disease. Blackwell Scientific, OxfordGoogle Scholar
  318. Stanbury SW, Lumb GA (1962) Metabolic studies of renal osteodystrophy. I. Calcium, phosphorus and nitrogen metabolism in rickets, osteomalacia and hyperparathyreoidism complicating chronic uremia and the osteomalacia of the adult Fanconi syndrome. Medicine (Baltimore) 41:1.Google Scholar
  319. Steendijk R (1971) Metabolic bone disease in children. Clin Orthop 77:247.PubMedGoogle Scholar
  320. Steinbach HL, Gordan G, Eisenberg E, Crane JT, Silverman S, Goldman L (1961) Primary hyperparathyreoidism: a correlation of roentgen, clinical and pathological features. Am J Roentgenol 86:329.Google Scholar
  321. Steinbach HL, Noetzli M (1964) Roentgen appearance of the skeleton in osteomalacia and rickets. Am J Roentgenol 91:955.Google Scholar
  322. Stickler GB (1976) Growth failure in renal disease. In: Symposium on Pediatric Nephrology. Chan JCM (ed) Pediatr Clin North Am 23:885.Google Scholar
  323. Swoboda W (1969) Das Skelett des Kindes. Thieme, StuttgartGoogle Scholar
  324. Taillard W (1964) Anatomie und Pathophysiologie der Epiphysiolysis capitis femoris. In: Die Epiphysiolysis capitis femoris, vol 21. Documenta Geigy, Basel, p 15Google Scholar
  325. Tanaka Y, De Luca HF (1973) The control of 25-hydroxy vitamin D metabolism by inorganic phosphorus. Arch Biochem Biophys 154:566.PubMedGoogle Scholar
  326. Tanner JM, Whitehouse RH, Marshall WA, Healy MJR, Goldstein H (1975) Assessment of skeletal maturity and prediction of adult height (TW2 method). Academic Press, LondonGoogle Scholar
  327. Tatler GLV, Baillod RA, Varghese J, Young WB, Farrow S, Wills MR, Moorhead JB (1973) Evolution of bone disease over 10 years in 135 patients with terminal renal failure. Br Med J 4:315.PubMedCentralPubMedGoogle Scholar
  328. Teall CG (1928) Radiological study of bone changes in renal infantilism. Br J Radiol 1:49.Google Scholar
  329. Teall CG (1954) Some observations on the radiology of Lignac-Fanconi disease and renal infantilism. Br J Radiol 27:618.PubMedGoogle Scholar
  330. Templeton AW, Jaconette JR, Ormond RS (1962) Localized osteosclerosis in hyperparathyreoidism. Am J Roentgenol 88:955Google Scholar
  331. Teplick JG, Eftekhari F, Haskin ME (1974) Erosion of the sternal ends of the clavicles. Radiology 113:323PubMedGoogle Scholar
  332. Tieder M, Stark H (1979) Forme familiale d’hypercalciurie idiopathique avec nanisme, atteinte osseuse et rénale chez l’enfant. Helv Paediatr Acta 34:359.PubMedGoogle Scholar
  333. Toni G de (1933) Remarks on the relations between renal rickets (renal dwarfism) and renal diabetes. Acta Paediatr 16:419.Google Scholar
  334. Toni G de (1956) Renal rickets with phospho-glucoamino renal diabetes. De-Toni-Debré Fanconi syndrome. Ann Paediatr (Basel) 187:42.Google Scholar
  335. Tschöpe W, Ritz E, Bommer J, Krempien B, Andrassy K, Mehls O (1973) Wirbelkörperprolaps bei Dialyse-Ostéopathie. Dtsch Med Wochenschr 98:1471.PubMedGoogle Scholar
  336. Uittenbogaart CH, Isaacson AS, Stanley P, Pennisi AJ, Malekzadeh MH, Ettenger RB, Fine RN (1978) Aseptic necrosis after renal transplantation in children. Am J Dis Child 132:165.Google Scholar
  337. Valvassori GE, Pierce RH (1964) Osteosclerosis in chronic uremia. Radiology 82:385.PubMedGoogle Scholar
  338. Vertuno LL, Preuss HG, Argy WP Jr, Schreiner GE (1974) Fanconi syndrome following homotrans-plantation. Arch Intern Med 133:302.PubMedGoogle Scholar
  339. Villanueva AR, Ilnicki L, Duncan E (1966) Bone and cell dynamics in osteoporosis: a review of measurements by tetracycline bone labelling. Clin Orthop 49:135.PubMedGoogle Scholar
  340. Walling MW (1977) 1,25 Dihydroxyvitamin D3 and intestinal phosphate absorption. In: Norman AW, Schaefer K, Coburn JW, DeLuca HF, Fraser DR, Grigoleit HG, Herrath D von (eds) Vitamin D: biochemical, chemical and clinical aspects related to calcium metabolism. De Gruyter, Berlin, p 321Google Scholar
  341. Weiss A (1972) Technique for demonstrating fine detail in bones of hands. Clin Radiol 23:185.PubMedGoogle Scholar
  342. Weiler M, Edeiken J, Hodes PhJ (1968) Renal osteodystrophy. Am J Roentgenol 104:354.Google Scholar
  343. West CD, Smith WC (1956) An attempt to elucidate the cause of growth retardation in renal disease. Am J Dis Child 91:460.Google Scholar
  344. Wilson DR, Siddiqui AA (1973) Renal tubular acidosis after kidney transplantation. Natural history and significance. Ann Int Med 79:352.PubMedGoogle Scholar
  345. Wilson RE, Bernstein DS, Murray JE, Moore FD (1965) Effects of parathyroidectomy and kidney transplantation on renal osteodystrophy. Am J Surg 110:384.PubMedGoogle Scholar
  346. Wilson SAK (1912) Progressive lenticular degeneration; a familial nervous disease associated with cirrhosis of the liver. Brain 34:295.Google Scholar
  347. Windaus A, Lettre H, Schenck F (1935) 7-Dehydro-cholesterol. Ann 520:98.Google Scholar
  348. Wolfe JN (1969) Xeroradiography of the bones, joints and soft tissue. Radiology 93:583.PubMedGoogle Scholar
  349. Wood BSB, Gerorge WH, Robinson AW (1958) Parathyroid adenoma in a child presenting as rickets. Arch Dis Child 33:46.PubMedGoogle Scholar
  350. Woolf LI (1966a) Inborn hepato-renal dysfunction. In: Gjessing LR (ed) Symposium on Tyrosinosis. In Honour of Dr. Grace Medes, 2.–3. June 1965. Universiteitsforlaget, Oslo, pp 82Google Scholar
  351. Woolf LI (1966b) Renal tubular dysfunction. Thomas, SpringfieldGoogle Scholar
  352. Zimmermann HB (1962) Osteosclerosis in chronic renal disease. — Report of 4 cases associated with secondary hyperparathyroidism. Am J Roentgenol 88:1152.Google Scholar

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© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • O. Mehls
  • H.-C. Oppermann

There are no affiliations available

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