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Bakterielle Kontamination von Blutkomponenten

  • Thomas Montag
  • H. Lange
  • U. Schmidt
  • J. Strobel
  • M. Exner
Chapter

Zusammenfassung

Seitdem im Jahre 1915 ein Fall von Syphilis-Übertragung durch Bluttransfusion publiziert wurde, ist die Diskussion um die transfusionsassoziierte bakterielle Infektion nicht mehr verstummt. Nachdem diese Problematik angesichts der Virusinfektionen durch Blut und Blutprodukte über einige Zeit etwas in den Hintergrund geraten war, erfuhr sie in der Literatur der letzten Jahre wieder die erforderliche Aufmerksamkeit. In dieser Arbeit wird die aktuelle Situation hinsichtlich der Kontaminationsraten von Blutkomponenten und der Häufigkeit von transfusionsbedingten bakteriellen Infektionen dargestellt. Das Spektrum der involvierten Keime wird diskutiert. Weiterhin werden die heutigen präventiven und diagnostischen Möglichkeiten sowie die Verfahren zur Inaktivierung von Bakterien einer kritischen Wertung unterzogen.

Bacterial contamination of blood components

Summary

Since the publication of a case of Syphilis transmission by blood transfusion in 1915 the discussion about transfusion-associated bacterial infection is ongoing. For some time, virus infections through blood and blood products have been highlighted. However, in the last years the attention required has been drawn to the problem of transmission of bacteria. In this publication the present situation concerning the contamination rates through blood components and the frequency of transfusion-associated microbial infections is outlined. The bacteria involved are discussed. Furthermore, the state of the art for prevention and diagnosis as well as the methods for inactivation of bacteria are assessed.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • Thomas Montag
    • 1
  • H. Lange
    • 1
  • U. Schmidt
    • 1
  • J. Strobel
    • 1
  • M. Exner
    • 2
  1. 1.Paul-Ehrlich-InstitutLangenDeutschland
  2. 2.Hygiene-Institut der Universität BonnDeutschland

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