Infections Due to the Dimorphic Fungi

  • T. S. Harrison
  • S. M. Levitz
Part of the The Mycota book series (MYCOTA, volume 6)


The thermally dimorphic fungi grow as molds in the natural environment or in the laboratory at 25–30°C, and as yeasts or spherules in tissue or when incubated on enriched media at 37 °C. They include the agents of the endemic systemic mycoses prevalent in the Western Hemisphere, i.e., Coccidioides immitis, Histoplasma capsulatum, Blastomyces dermatitidis, and Paracoccidioides brasiliensis. Also discussed here are Sporothrix schenckii, which occurs worldwide and usually causes cutaneous rather than systemic disease, and Pénicillium marneffei, a recently recognized cause of systemic mycosis in Southeast Asia. In recent years, these fungi have become an increasing problem due to rising populations in the endemic areas, more travel, and an increasing number of immunocompromised patients (especially those with AIDS). Because of space limitations we have tried to emphasize more recent developments in the ecology, epidemiology, and clinical aspects of these mycoses. Pathogenesis and host defense are reviewed in other chapters (Chaps. 1, 3, 4, this Vol.).


Endemic Area Yeast Form Dimorphic Fungus Histoplasma Capsulatum Mycosis Study Group 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • T. S. Harrison
    • 1
  • S. M. Levitz
    • 1
  1. 1.Section of Infectious Diseases, Evans Memorial Department of Clinical Research and Department of MedicineBoston University School of MedicineBostonUSA

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