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Endokrine Funktionen II: Zytokine

  • P. C. Heinrich
  • F. Schaper
  • A. Timmermann
  • A. S. Martens
  • U. Lehmann
Chapter
Part of the Springer-Lehrbuch book series (SLB)

Zusammenfassung

Zytokine werden von den meisten Körperzellen nach Stimulation synthetisiert und sezerniert. Sie wirken in der Regel lokal über Oberflächenrezeptoren und aktivieren Signaltransduktionskaskaden, die zu veränderter Genexpression, Stoffwechselaktivität, Zelldifferenzierung, Proliferation, Migration und Apoptose führen können. Unterschiedliche Zytokine können die gleiche Signaltransduktionskaskase aktivieren (Redundanz).Andererseits kann ein bestimmtes Zytokin auf verschiedene Zelltypen einwirken und unterschiedliche Antworten hervorrufen (Pleiotropie).

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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • P. C. Heinrich
  • F. Schaper
  • A. Timmermann
  • A. S. Martens
  • U. Lehmann

There are no affiliations available

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