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Bipolare Erkrankungen — sind moderne Neuroleptika eine neue Option?

  • Heinz Grunze
Conference paper

Zusammenfassung

Der Heterogenität bipolarer Störungen Rechnung tragend, wurden in den letzten Jahren verschiedene Alternativen zur bisherigen Standardtherapie Lithium entwickelt. Neben Antiepileptika kommen zunehmend auch moderne Neuroleptika zum Einsatz, von denen insbesondere die Patienten profitieren, bei denen traditionell verwendete Stimmungs- stabilisierer nicht den gewünschten Therapieerfolg brachten.

Literaturs

  1. 1.
    Angst J, Marneros A (2001) Bipolarity from ancient to modern times: conception, birth and rebirth. J Affect Disord 67: 3–19PubMedCrossRefGoogle Scholar
  2. 2.
    Strakowski SM et al. (1998) Course of psychiatric and substance abuse syndromes co-occurring with bipolar disorder after a first psychiatric hospitalization. J Clin Psychiatry 59(9): 465–471PubMedCrossRefGoogle Scholar
  3. 3.
    Goodwin FK, Jamison KR (1990) Manic-depressive illness. New York, Oxford University PressGoogle Scholar
  4. 4.
    Frye MA et al. (2000) The increasing use of polypharmacotherapy for refractory mood disorders: 22 years of study. J Clin Psychiatry 61: 9–15PubMedCrossRefGoogle Scholar
  5. 5.
    Tohen M et al. (1999) Olanzapine in the treatment of mania: a double-blind, placebo-controlled four week study. Eur Neuropsychopharmacol (9 Suppl) 5: 247Google Scholar
  6. 6.
    Tohen M et al. (2000) Efficacy of olanzapine in acute bipolar mania: a double-blind, placebo-controlled study. The Olanzapine HGGW Study Group. Arch Gen Psychiatry 57: 841–849PubMedCrossRefGoogle Scholar
  7. 7.
    Tohen M et al. (2002) Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy. Arch Gen Psychiatry 59: 62–69PubMedCrossRefGoogle Scholar
  8. 8.
    Sanger TM et al. (2001) Long-term olanzapine therapy in the treatment of bipolar I disorder: an open-label continuation phase study. J Clin Psychiatry 62: 273–281PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Heinz Grunze
    • 1
  1. 1.MünchenDeutschland

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