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Verhandlungen pp 1467-1469 | Cite as

Identification and subsequent studies of foot-and-mouth disease virus

  • S. S. BreeseJr.
  • H. L. Bachrach
Chapter

Abstract

Foot-and-mouth disease virus, type A, strain 119, (FMDV-A 119) was purified from infectious tissue culture fluid, bovine vesicular fluid, and tongue epithelium and identified by analytical electron microscopy as a particle approximately 23 mμ in diameter. In addition, a smaller particle (8 ± 2 mμ) closely associated with the virus particle, particularly in animal-derived material, was found in centrifugally-separated fractions which possessed complement-fixing activity.

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References

  1. 1.
    Bachrach, H. L., and S. S. Breese jr.: Proc. Soc. exp. Biol. (N. Y.) 97, 659 (1958).CrossRefGoogle Scholar
  2. 2.
    Steere, R. L.: J. biophys. biochem. Cytol. 3, 45 (1957).CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1960

Authors and Affiliations

  • S. S. BreeseJr.
    • 1
  • H. L. Bachrach
    • 1
  1. 1.Plum Island Animal Disease Laboratory, Animal Disease and Parasite Research Division, Agricultural Research ServiceUS-Department of AgricultureGreenportUSA

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