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Model fitting is employed in numerous medical imaging applications for quantitative parameter estimation. Prominent examples include pharmacokinetic modelling of dynamic contrast-enhanced (DCE) MRI data and apparent diffusion coefficient calculations. There are many fitting tools available, however most of them are limited to a special purpose and do not allow for own development and extension.
- 1.Floca R, Debus C, Ingrisch M, et al. MITK-ModelFit: A generic open-source framework for model fits and their exploration in medical imaging - design, implementation and application on the example of DCE-MRI. BMC Bioinformatics. 2019;20(21).Google Scholar