K Virus Infection, Liver, Mouse

  • John E. Greenlee
Part of the Monographs on Pathology of Laboratory Animals book series (LABORATORY)


Livers of infected animals, even those of suckling mice with fatal infection, are grossly normal.


None. However K virus is also referred to as K-papovavirus 


  1. Domes K, Johnson RT, ter Meulen V (1979) Detection of Polyomavirus DNA in PML-brain tissue by (in situ) hybridization. J Gen Virol 42:49–57CrossRefGoogle Scholar
  2. Fisher ER, Kilham L (1953) Pathology of a pneumotrope virus recovered from C3H mice carrying the Bittner milk agent. Arch Pathol 55:14–19Google Scholar
  3. Gleiser CA, Heck FC (1972) The pathology of experimental K-virus infection in suckling mice. Lab Anim Sci 22: 865–869PubMedGoogle Scholar
  4. Greenlee JE (1979) Pathogenesis of K virus infection in newborn mice. Infect Immun 26: 705–713PubMedGoogle Scholar
  5. Greenlee JE (1981) Effect of host age on experimental K virus infection in mice. Infect Immun 33: 297–303PubMedGoogle Scholar
  6. Greenlee JE (1983) Pathogenesis of K virus infection in mice. In: Sever JL, Madden D (eds) Polyomaviruses and human neurological disease. Liss, New York, pp 325–342Google Scholar
  7. Greenlee JE, Keeney PM (1982) Immunofluorescent labelling of K-papovavirus antigens in glycol methacry-late embedded material: a method for studying infected cell populations by fluorescence microscopy and histological staining of adjacent sections. Stain Technol 57: 197–205PubMedGoogle Scholar
  8. Holt D (1959) Presence of K virus in wild mice in Australia. Aust J Exp Biol Med Sci 37:183–192PubMedCrossRefGoogle Scholar
  9. Jordan SW, Doughty WE (1969) Ultrastructural pathology of murine pneumonitis caused by K-papovavirus. Exp Mol Pathol 11:1–7PubMedCrossRefGoogle Scholar
  10. Kilham L, Murphy HW (1953) A pneumotropic virus isolated from C3H mice carrying the Bittner milk agent. Proc Soc Exp Biol Med 82:133–137PubMedGoogle Scholar
  11. McCance DJ, Sebesteny A, Griffin BE, Balkwill F, Tilly R, Gregson NA (1983) A paralytic disease in nude mice associated with polyoma virus infection. J Gen Virol 64: 57–67PubMedCrossRefGoogle Scholar
  12. Mokhtarian F, Shah KV (1980) Role of antibody response in recovery from K-papovavirus infection in mice. Infect Immun 29:1169–1179PubMedGoogle Scholar
  13. Mokhtarian F, Shah KV (1983) Pathogenesis of K papo-vavirus infection in athymic nude mice. Infect Immun 41:434–436PubMedGoogle Scholar
  14. Parker JC, Tennant RW, Ward TG (1966) Prevalence of viruses in mouse colonies: K virus. Natl Cancer Inst Mo-nogr 20:33Google Scholar
  15. Rowe WP, Hartley JW, Huebner RJ (1963) Polyoma and other indigenous mouse viruses. Lab Anim Care 13 (Part 2): 166–175PubMedGoogle Scholar
  16. Sheffield WD, Strandberg JD, Braun L, Shah K, Kalter SS (1980) Simian virus 40-associated fatal interstitial pneumonia and renal tubular necrosis in a rhesus monkey. J Infect Dis 142: 618–622PubMedCrossRefGoogle Scholar
  17. Tennant RW, Parker JC, Ward TG (1966) Respiratory virus infections of mice: K virus. Natl Cancer Inst Monogr 20:100–104Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • John E. Greenlee

There are no affiliations available

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