Rat Coronavirus Infection, Lung, Rat

  • David G. Brownstein
Part of the Monographs on Pathology of Laboratory Animals book series (LABORATORY)


Naturally infected adult rats rarely have grossly observable changes. Experimentally infected 9–10 week old axenic rats develop gross lesions in the lung on postinoculation days 6 and 7, which consist of randomly dispersed red-brown to gray foci, less than 1 mm in diameter (Bhatt and Jacoby 1977). Although rat coronavirus may cause fatal pneumonia in a high percentage of newborn and day-old rats, gross pulmonary lesions have not been described (Parker et al. 1970).


Interstitial Pneumonia Infectious Bronchitis Virus Sendai Virus Pneumonia Virus Lung Change 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • David G. Brownstein

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