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Rat Coronavirus Infection, Lung, Rat

  • David G. Brownstein
Chapter
Part of the Monographs on Pathology of Laboratory Animals book series (LABORATORY)

Abstract

Naturally infected adult rats rarely have grossly observable changes. Experimentally infected 9–10 week old axenic rats develop gross lesions in the lung on postinoculation days 6 and 7, which consist of randomly dispersed red-brown to gray foci, less than 1 mm in diameter (Bhatt and Jacoby 1977). Although rat coronavirus may cause fatal pneumonia in a high percentage of newborn and day-old rats, gross pulmonary lesions have not been described (Parker et al. 1970).

Keywords

Interstitial Pneumonia Infectious Bronchitis Virus Sendai Virus Pneumonia Virus Lung Change 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Bhatt PN, Jacoby RO (1977) Experimental infection of adult axenic rats with Parker’s rat coronavirus. Arch Virol 54: 345–352PubMedCrossRefGoogle Scholar
  2. Bhatt PN, Percy DH, Jonas AM (1972) Characterization of the virus of sialodacryoadenitis of rats: a member of the coronavirus group. J Infect Dis 126: 123–130PubMedCrossRefGoogle Scholar
  3. Bohl EH (1981) Coronaviruses: diagnosis of infections. In: Kurstak E, Kurstak C (eds) Comparative diagnosis of viral diseases, vol 4. Academic, New York, chap 7Google Scholar
  4. Jacoby RO, Bhatt PN, Jonas AM (1979) Viral diseases. In: Baker HJ, Lindsey JR, Weisbroth SH (eds) The laboratory rat, vol 1. Academic, New York, chap 11Google Scholar
  5. Jonas AM, Craft J, Black CL, Bhatt PN, Hilding D (1969) Sialodacryoadenitis in the rat. A light and electron microscopic study. Arch Pathol 88: 613–622Google Scholar
  6. Parker JC, Cross SS, Rowe WP (1970) Rat coronavirus (RCV): a prevalent, naturally occurring pneumotropic virus of rats. Arch Virusforsch 31: 293–302PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • David G. Brownstein

There are no affiliations available

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