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Murine Respiratory Mycoplasmosis, Upper Respiratory Tract, Rat

  • Trenton R. Schoeb
  • J. Russell Lindsey
Chapter
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Part of the Monographs on Pathology of Laboratory Animals book series (LABORATORY)

Abstract

Some affected rats have mucopurulent nasal exudate or pink, porphyrin-tinted oculonasal discharge, but gross lesions in the upper respiratory tract are, in many cases, not detectable. Exudate can sometimes be found in the nasal passages, trachea, and tympanic cavities. These structures should be disturbed as little as possible during dissection and collection of specimens for culture so as to preserve the quality of the tissues for microscopic examination.

Keywords

Nasal Passage Sendai Virus Tympanic Cavity Goblet Cell Hyperplasia Mycoplasma Gallisepticum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Broderson JR, Lindsey JR, Crawford JE (1976) The role of environmental ammonia in respiratory mycoplasmosis of rats. Am J Pathol 85: 115–130PubMedGoogle Scholar
  2. Cassell GH, Davis JK, Wilborn WH, Wise KS (1978) Pathobiology of mycoplasmas. In: Schlessinger D (ed) Microbiology 1978. American Society for Microbiology, Washington DC, pp 399–403Google Scholar
  3. Cassell GH, Lindsey JR, Baker HJ, Davis JK (1979) Mycoplasmal and rickettsia] diseases. In: Baker HJ, Lindsey JR, Weisbroth SH (eds) The laboratory rat, vol 1. Academic, New York, chap 10Google Scholar
  4. Cassell GH, Lindsey JR, Davis JK, Davidson MK, Brown MB, Mayo JG (1981) Detection of natural Mycoplasma pulmonis infection in rats and mice by an enzyme linked immunosorbent assay (ELISA). Lab Anim Sci 31: 676–682PubMedGoogle Scholar
  5. Davidson MK, Lindsey JR, Brown MB, Schoeb TR, Cassell GH (1981) Comparison of methods for detection of Mycoplasma pulmonis in experimentally and naturally infected rats. J Clin Microbiol 14: 646–655PubMedGoogle Scholar
  6. Davis JK, Cassell GH (1982) Murine respiratory mycoplasmosis in LEW and F344 rats: strain differences in lesion severity. Vet Pathol 19: 280–293PubMedCrossRefGoogle Scholar
  7. Davis JK, Thorp RB, Maddox PA, Brown MB, Cassell GH (1982) Murine respiratory mycoplasmosis in F344 and LEW rats: evolution of lesions and lung lymphoid cell populations. Infect Immun 36: 720–729PubMedGoogle Scholar
  8. Del Giudice RA, Gardella RS, Hopps HE (1980) Cultivation of formerly noncultivable strains of Mycoplasma hyorhinis. Curr Microbiol 4: 75–80CrossRefGoogle Scholar
  9. Ganaway JR, Allen AM, Moore TD, Bohner HJ (1973) Natural infection of germ-free rats with Mycoplasma pulmonis. J Infect Dis 127: 529–537PubMedCrossRefGoogle Scholar
  10. Horowitz SA, Cassell GH (1978) Detection of antibodies to Mycoplasma pulmonis by an enzyme linked immunosorbent assay. Infect Immun 22: 161–170PubMedGoogle Scholar
  11. Howard CJ, Stott EJ, Taylor G (1978) The effect of pneumonia induced in mice with Mycoplasma pulmonis on resistance to subsequent bacterial infection and the effect of a respiratory infection with Sendai virus on the resistance of mice to Mycoplasma pulmonis. Gen Microbiol 109: 79–87Google Scholar
  12. Jacoby RO, Bhatt PN, Jonas AM (1979) Viral diseases. In: Baker HJ, Lindsey JR, Weisbroth SH (eds) The laboratory rat, vol 1. Academic, New York, chap 11Google Scholar
  13. Jakab GJ (1981) Interactions between Sendai virus and bacterial pathogens in the murine lung: a review. Lab Anim Sci 31: 170–177PubMedGoogle Scholar
  14. Kaklamanis E, Stavropoulos K, Thomas L (1971) The mycoplasmacidal action of homogenates of normal tissues. In: Madoff S (ed) Mycoplasma and the L-forms of bacteria. Gordon and Breach, New York, pp 27–35Google Scholar
  15. Mardh PA, Taylor-Robinson D (1973) New approaches to the isolation of mycoplasmas. Med Mikrobiol Immunol (Berl) 158: 259–266CrossRefGoogle Scholar
  16. Naot Y, Merchav S, Ben-David E, Ginsburg H (1979) Mitogenic activity of Mycoplasma pulmonis. I. Stimulation of rat B and T lymphocytes. Immunology 36: 399–406PubMedGoogle Scholar
  17. Schoeb TR, Davidson MK, Lindsey JR (1982) Intracage ammonia promotes growth of Mycoplasma pulmonis in the respiratory tract of rats. Infect Immun 38: 212–217PubMedGoogle Scholar
  18. Tauraso NM (1967) Effect of diethylaminoethyl dextran on the growth of mycoplasma in agar. J Bacteriol 93: 1559–1564PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • Trenton R. Schoeb
  • J. Russell Lindsey

There are no affiliations available

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