Apparent Absence of Dosage Compensation for Z-linked Genes of Avian Species

  • Susumu Ohno
Part of the Monographs on Endocrinology book series (ENDOCRINOLOGY, volume 1)


Although the two are rather similar in absolute size, the avian Z-chromosome makes up nearly 10% of the genome, while the original X of placental mammals comprises only 5%. It would appear that birds have an even greater need than mammals for developing an effective dosage compensation mechanism for their Z-linked genes. It is a great surprise to find that avian species apparently failed in developing an effective means for achieving the dosage compensation.


Avian Species Dosage Compensation Domestic Chicken Heterozygous Male Dosage Compensation Mechanism 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1966

Authors and Affiliations

  • Susumu Ohno
    • 1
  1. 1.Department of BiologyCity of Hope MedicalDuarteUSA

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