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Nosocomial Infections in the Intensive Care Unit

  • Paul Ellis Marik
Chapter
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Abstract

Catheter-associated sepsis is defined as bloodstream infection due to an organism that has colonized a vascular catheter. Approximately 5% of patients with indwelling vascular catheters (uncoated) will develop bloodstream infection (≈10 infections per 1000 catheter days). The incidence of catheter-associated sepsis increases with the length of time the catheter is in situ, the number of ports, and the number of manipulations. Approximately 25% of catheters become colonized (>15 colony-forming units, CFU) and approximately 20% to 30% of colonized catheters will result in catheter sepsis. Staphylococcus aureus and coagulase-negative staphylococci are the most common infecting (and colonizing) organisms, followed by enterococci, gram-negative bacteria, and Candida species. Antibiotic-coated catheters significantly reduce catheter colonization and catheterassociated bloodstream infection. Femoral catheters are not associated with a higher infection rate. Similarly, neither the type of occlusive dressing nor the frequency of dressing change affects the incidence of catheter-associated sepsis.

Keywords

Nosocomial Infection Candida Species Invasive Candidiasis Acalculous Cholecystitis Maxillary Sinusitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York, Inc. 2001

Authors and Affiliations

  • Paul Ellis Marik
    • 1
  1. 1.Critical Care MedicineMercy Hospital of PittsburghPittsburghUSA

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