Adjuvante intraoperative Strahlentherapie (IORT) beim Magenkarzinom
Adjuvant Intraoperative Radiation Therapy (IORT) for Gastric Cancer
In order to evaluate the role of adjuvant IORT in the treatment of resectable gastric carcinoma, we carried out a randomized trial comparing surgery and surgery + adjuvant IORT. The study included 115 patients within a 74-month period, 51 of them received a single application of 28 Gy to the celiac axis. Patients were comparable with regard to age, sex, tumor stage and operative morbidity. The difference in mean survival time (IORT: 26.9 months vs. non-IORT: 30.8 months) and tumor-related death in the long-term course (mean follow-up period 29.2 months) with 29.4% (15/51) in the IORT-treated patients vs. 31.2% (20/64) in non-irradiated patients did not reach significance.
Key wordsIntraoperative radiation therapy IORT Stomach neoplasms Gastric cancer Adjuvant therapy Randomized controlled clinical trial
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