Transfusion Requirements in Critical Care: A Multicenter Controlled Clinical Trial

  • P. C. Hébert
Conference paper
Part of the Yearbook of Intensive Care and Emergency Medicine book series (YEARBOOK, volume 1998)


Anemia is common in the critically ill and results in the frequent use of red cell transfusions [1, 2]. For decades, an arbitrary transfusion threshold of 100 g/L has been employed widely in clinical medicine including the management of critically ill patients [3]. Recently, a re-evaluation of this practice was prompted both by the fear of transfusion-related infections such as aquired immune deficiency syndrome (AIDS), and the prospect of an ever decreasing blood supply [4–6]. These concerns also resulted in the formulation of red cell transfusion guidelines by a number of organizations for the use of red cells [7–10]. However, published guidelines, for the most part, have not addressed how red cells should be administered in critically ill patients.


Oxygen Delivery Transfusion Requirement Adult Respiratory Distress Syndrome Transfusion Practice Transfusion Strategy 
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  • P. C. Hébert

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