Whither the WBC Differential?—Some Alternatives
Most efforts to automate the WBC differential have involved the use of devices to identify and enumerate WBC types, the underlying assumption being that the cell type percentages constitute the important end result.
Determination of linked abnormalities on 117,000 WBC counts and presentation of linkages to the morphologist when a particular abnormality was identified on the hemogram or the slide.
Information feedback which compared each technologist with others in the laboratory performing similar tasks.
Varying the number of cells examined per slide, based on the apparent abnormality of the slide.
The linkage patterns found, their clinical usefulness, and the impact on technologist performance and test quality are discussed.
Key WordsLeukocytes White cells Differential Automation Linked abnormalities
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