Ektacytometric Analysis of Factors Regulating Red Cell Deformability
Photometric analysis of laser diffraction patterns has been used to obtain quantitative measurements of deformability of specifically modified normal red cells. Variation of deformability with suspending medium osmolality and with applied shear stress was used to distinguish between changes in internal viscosity, surface area-to-volume ratio, and viscoelastic properties of the membrane in their influence on whole cell deformability.
Key WordsRed cell deformability Laser diffractometry Internal viscosity Membrane material properties.
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