Positron-Emission Tomography and Cerebral Metabolism

  • D. Comar
  • M. Mazière
  • J. M. Saudubray
  • E. Zarifian
  • R. Naquet
Conference paper


The association of new methods of labelling with short-lived radio-isotopes and of visualisation “in vivo” of these labelled molecules by emission tomography allows study of the brain metabolism at different levels : fluid movements (cerebral blood-flow), metabolism (oxygen or glucose consumption), blood-brain barrier permeability, metabolism of drugs (receptor ligand interactions). The success of such investigations depends on the simultaneous availability of three technological development : production of the chosen radio-isotope ; the labelling procedure and the detection device.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1980

Authors and Affiliations

  • D. Comar
  • M. Mazière
  • J. M. Saudubray
  • E. Zarifian
  • R. Naquet

There are no affiliations available

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