Animal Models in Periodontal Research

  • Alexandrina L. Dumitrescu


Animal models have been used to evaluate the pathogenesis of periodontal diseases and various periodontal treatment modalities. Human longitudinal studies of periodontal diseases pose many problems such as determining the level of disease activity, individuals at risk and susceptibility to disease progression. It is important to choose a laboratory animal model that has similar characteristics of human anatomy and periodontal disease. Features of periodontal diseases in humans and animals vary greatly depending upon which form of the disease is present and the stage of the development. Inflammatory destruction of the periodontium can be spontaneous or experimentally induced in most mammalian species.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Alexandrina L. Dumitrescu
    • 1
    • 2
  1. 1.Department of PeriodontologyUniversity of Tromsø Institute of Clinical DentistryTromsøNorway
  2. 2.Private practiceBucharestRomania

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