Clinical Trial Principles for Evaluation of Products Used in the Management of Oral Malodour

  • Alexandrina L. Dumitrescu


Halitosis is a general term used to define an unpleasant or offensive odour emanating from the breath regardless of whether the odour originates from oral or non-oral sources. Other terms used are bad or foul breath, breath malodour, oral malodour, foetor ex ore, and foetor oris. Halitosis is widespread and is believed to affect one-quarter of the population around the world, and most people have this condition from time to time. Those affected are usually unaware of their condition possibly because of smell adaptation. Another explanation could be the pathways between the inhaled and exhaled air diverge—because the expelled air from the mouth travels horizontally, whereas the air breathed in travels primarily vertically; there is a lowered chance of detecting the smell from the expelled air.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Alexandrina L. Dumitrescu
    • 1
    • 2
  1. 1.Department of PeriodontologyUniversity of Tromsø Institute of Clinical DentistryTromsøNorway
  2. 2.Private practiceBucharestRomania

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